ID E3REF5_PYRTT Unreviewed; 593 AA.
AC E3REF5;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Transcriptional repressor Tup1 N-terminal domain-containing protein {ECO:0000259|Pfam:PF08581};
GN ORFNames=PTT_04388 {ECO:0000313|EMBL:EFQ95887.1};
OS Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus)
OS (Drechslera teres f. teres).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=861557 {ECO:0000313|Proteomes:UP000001067};
RN [1] {ECO:0000313|EMBL:EFQ95887.1, ECO:0000313|Proteomes:UP000001067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0-1 {ECO:0000313|EMBL:EFQ95887.1,
RC ECO:0000313|Proteomes:UP000001067};
RX PubMed=21067574; DOI=10.1186/gb-2010-11-11-r109;
RA Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., Moffat C.S.,
RA Oliver R.P., Friesen T.L.;
RT "A first genome assembly of the barley fungal pathogen Pyrenophora teres f.
RT teres.";
RL Genome Biol. 11:R109.1-R109.14(2010).
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DR EMBL; GL532432; EFQ95887.1; -; Genomic_DNA.
DR RefSeq; XP_003296010.1; XM_003295962.1.
DR AlphaFoldDB; E3REF5; -.
DR STRING; 861557.E3REF5; -.
DR EnsemblFungi; EFQ95887; EFQ95887; PTT_04388.
DR KEGG; pte:PTT_04388; -.
DR eggNOG; KOG0266; Eukaryota.
DR HOGENOM; CLU_000288_57_23_1; -.
DR OrthoDB; 91476at2759; -.
DR Proteomes; UP000001067; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR GO; GO:0017053; C:transcription repressor complex; IEA:EnsemblFungi.
DR GO; GO:0042393; F:histone binding; IEA:EnsemblFungi.
DR GO; GO:0042826; F:histone deacetylase binding; IEA:EnsemblFungi.
DR GO; GO:0036033; F:mediator complex binding; IEA:EnsemblFungi.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:EnsemblFungi.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:EnsemblFungi.
DR GO; GO:0000433; P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose; IEA:EnsemblFungi.
DR GO; GO:0006974; P:DNA damage response; IEA:EnsemblFungi.
DR GO; GO:0006972; P:hyperosmotic response; IEA:EnsemblFungi.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:EnsemblFungi.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR013890; Tscrpt_rep_Tup1_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08581; Tup_N; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001067};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 19..87
FT /note="Transcriptional repressor Tup1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08581"
FT REPEAT 337..371
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 372..413
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 420..454
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 458..499
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 512..544
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 554..593
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 64..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..166
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..225
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 64314 MW; 42C8B2A0D439363D CRC64;
MNHYPPRVMG GPQAGPAQRL NELLDNIKTE FETESQRSAE YEGQITRHIQ EIELIRGKVY
SLEQSHNQMK SKYEERIAQL ERELEARGGP SQNSQHHGPS QPQPPQIGHG PSNLFGGIMA
GSAAQGGPGL APPPQEPPQG HGMPPQLGGP QGPPGPPGPP QHFGGYQPGP PSVNGYGQPP
QPTASPGAKR PGPARGPPNP ATPQQNNPAP YPGSPQVPRP TPPPHHQQNA LMAANHIPLR
ESNILADLDI EQLPENLKKE GSDWFAVFNP RSRRVLDVDL IHNLPHQSVV CCVRFSLDGR
YVATGCNRSA QIFDVETGSP VAHLQDGSLP EDGDLYIRSV CFSPNGQYLA TGAEDKVIRV
WDIASRTIKH QFTGHEQDIY SLDFARNGKI IASGSGDRSV RLWDLESNMQ VSNFSIEDGV
TTVAISPDNL YVAAGSLDKS VRVWDIQTGQ LVVRLEGEHG HKDSVYSVAF APSGNRLVSG
SLDKTIKMWE LSTTNRFVPG GNHPTGKCVR TFEGHKDFVL SVALTPHGDW VLSGSKDRGV
QFWDPHTGVA QLMLQGHKNS VISVAPSPTG GVFATGSGDM RARIWRFDRY QGA
//
