ID E3RF23_PYRTT Unreviewed; 521 AA.
AC E3RF23;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Mate efflux family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PTT_05474 {ECO:0000313|EMBL:EFQ95679.1};
OS Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus)
OS (Drechslera teres f. teres).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=861557 {ECO:0000313|Proteomes:UP000001067};
RN [1] {ECO:0000313|EMBL:EFQ95679.1, ECO:0000313|Proteomes:UP000001067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0-1 {ECO:0000313|EMBL:EFQ95679.1,
RC ECO:0000313|Proteomes:UP000001067};
RX PubMed=21067574; DOI=10.1186/gb-2010-11-11-r109;
RA Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., Moffat C.S.,
RA Oliver R.P., Friesen T.L.;
RT "A first genome assembly of the barley fungal pathogen Pyrenophora teres f.
RT teres.";
RL Genome Biol. 11:R109.1-R109.14(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR EMBL; GL532587; EFQ95679.1; -; Genomic_DNA.
DR RefSeq; XP_003296228.1; XM_003296180.1.
DR AlphaFoldDB; E3RF23; -.
DR STRING; 861557.E3RF23; -.
DR EnsemblFungi; EFQ95679; EFQ95679; PTT_05474.
DR KEGG; pte:PTT_05474; -.
DR eggNOG; KOG1347; Eukaryota.
DR HOGENOM; CLU_012893_1_2_1; -.
DR OrthoDB; 661905at2759; -.
DR Proteomes; UP000001067; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206:SF113; MATE EFFLUX FAMILY PROTEIN (EUROFUNG); 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR Pfam; PF01554; MatE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001067};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 21..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56873 MW; 97DCADB0338C1C13 CRC64;
MDYETNKSRS WIPGFLRASK KDIDTPDERS PLLPDSHREE WSSGETYELD DEEASSSQLV
LREFWILLKG SLPVVVAYAL QNSLQTVSVL IVGRLSPEAL ATAAFSYMFA MATGWLVALG
GTTAIDTLAS ASFTGSKNPH DLGIILQRSF VVLSSFYVPI AILWFCSEPL FKALGQEDYI
ARDSARFLSV LAPGGIGYIY FEALKKYMQA QEIMRPGTYV LLITSPLSAG LNYLFVYTFK
MGLLGAPLAT GIAYWASFFL LLAYARFVNG WQCWGGWDCK CLQNSWIFAR LALLGVIHVG
TEWWAFEIVA LVAGKLGTIP LAAQSVIMTT DQVMNTIPFG VGVATSSRVG NLLGSRDAKG
AARAANTAAV LSMVLGVLVL AVLMGVKDFY AKIFNDDVEV IKLTAKVMPY VALFQIADGL
NGSCGGALRG MGRQHIGATV NIISYYCGAL PLGIWLAFHG WGLGGLWVGQ CIALYLVGFA
EWAIVAWSNW DYQVKKAFDR MDSDDRAEIG ISPEEATPVH R
//
