ID E3TE28_ICTPU Unreviewed; 240 AA.
AC E3TE28;
DT 11-JAN-2011, integrated into UniProtKB/TrEMBL.
DT 11-JAN-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Homeobox protein TGIF1 {ECO:0000313|RefSeq:NP_001187376.1};
DE SubName: Full=Homeobox protein akr {ECO:0000313|EMBL:ADO28564.1};
GN Name=AKR {ECO:0000313|EMBL:ADO28564.1};
GN Synonyms=akr {ECO:0000313|RefSeq:NP_001187376.1}, tgif1
GN {ECO:0000313|RefSeq:NP_001187376.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:ADO28564.1};
RN [1] {ECO:0000313|EMBL:ADO28564.1, ECO:0000313|RefSeq:NP_001187376.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20634964; DOI=10.1371/journal.pone.0011546;
RA Chen F., Lee Y., Jiang Y., Wang S., Peatman E., Abernathy J., Liu H.,
RA Liu S., Kucuktas H., Ke C., Liu Z.;
RT "Identification and characterization of full-length cDNAs in channel
RT catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus).";
RL PLoS ONE 5:E11546-E11546(2010).
RN [2] {ECO:0000313|RefSeq:NP_001187376.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=27307075;
RA Zeng Q., Liu S., Yao J., Zhang Y., Yuan Z., Jiang C., Chen A., Fu Q.,
RA Su B., Dunham R., Liu Z.;
RT "Transcriptome Display During Testicular Differentiation of Channel Catfish
RT (Ictalurus punctatus) as Revealed by RNA-Seq Analysis.";
RL Biol. Reprod. 95:19-19(2016).
RN [3] {ECO:0000313|RefSeq:NP_001187376.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR EMBL; GU588608; ADO28564.1; -; mRNA.
DR RefSeq; NP_001187376.1; NM_001200447.1.
DR STRING; 7998.ENSIPUP00000002200; -.
DR GeneID; 100528177; -.
DR KEGG; ipu:100528177; -.
DR CTD; 7050; -.
DR OrthoDB; 3180467at2759; -.
DR Proteomes; UP000221080; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR PANTHER; PTHR11850:SF59; HOMEOBOX PROTEIN TGIF1; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000313|RefSeq:NP_001187376.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 34..97
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 36..98
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 240 AA; 26422 MW; D27D2216E135605B CRC64;
MKPKKGMQAT SGSETEDEDN IDVPLDLSSS RGSAAKRKRR GNLPKESVQI LRDWLYEHRY
NAYPSEQEKA LLSKQTHLST LQVCNWFINA RRRLLPEMLR KDGKDPNQFT ISRRASKGPE
GMSDSSHSPK HDSYETGSPA CPDNTTIDTS YPRKNASPTL ARPSVICHTT ITAIGTNIEG
TTELAVFSCP SGTGLGTEFN TPPSTPPDLT AQDFSGFQLL VDVALKRAAE MELQAKRVLA
//
