ID E4KLQ8_9LACT Unreviewed; 402 AA.
AC E4KLQ8;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:EFR32060.1};
GN ORFNames=HMPREF9257_0890 {ECO:0000313|EMBL:EFR32060.1};
OS Eremococcus coleocola ACS-139-V-Col8.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Eremococcus.
OX NCBI_TaxID=908337 {ECO:0000313|EMBL:EFR32060.1, ECO:0000313|Proteomes:UP000005990};
RN [1] {ECO:0000313|EMBL:EFR32060.1, ECO:0000313|Proteomes:UP000005990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-139-V-Col8 {ECO:0000313|EMBL:EFR32060.1,
RC ECO:0000313|Proteomes:UP000005990};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR32060.1}.
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DR EMBL; AENN01000001; EFR32060.1; -; Genomic_DNA.
DR RefSeq; WP_006417542.1; NZ_AENN01000001.1.
DR AlphaFoldDB; E4KLQ8; -.
DR STRING; 908337.HMPREF9257_0890; -.
DR eggNOG; COG0025; Bacteria.
DR OrthoDB; 9790604at2; -.
DR Proteomes; UP000005990; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR31102; -; 1.
DR PANTHER; PTHR31102:SF1; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005990};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..383
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 402 AA; 43074 MW; CC09643531C7E278 CRC64;
MDFFLCLAIV LVVGGGAGYL FTKLRLPALL AYMLLGIVLG SLGLMNPQIL AVSGELRKIA
LIIILLKAGL SLDLEDLKKV GRPALLMSFL PCCIEMITIG IVSHFLLGLS FVEGFLLGAV
LGAVSPAVVV PRTSRLMDEG IGTDQGIPQM ITAASSMDDI VMIVFYTSFL TIEGGGAMKL
SSFMTIPVSI ITGILGGIVV GLIFAYLFDH VHLRDSMKLI ILLGTSFFLV YLENYLQDFI
AYSSLLSVIA MGMTLFFKTQ VRATRLKAKC DRLWVVSEIF LFTLVGASIQ INYALEVLGL
ALVTIIIGLI FRNIGVQLAI MGTQLDQKER TFMSIAYLPK ATVQAAIGGG LLDLGNQLNN
PAIINAGIIV LSVAVVAILF TAPLGAILMD LTYKGLLKAS KS
//
