ID E4KQB2_9LACT Unreviewed; 324 AA.
AC E4KQB2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=NAD dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:EFR30915.1};
DE EC=5.1.3.- {ECO:0000313|EMBL:EFR30915.1};
GN ORFNames=HMPREF9257_1713 {ECO:0000313|EMBL:EFR30915.1};
OS Eremococcus coleocola ACS-139-V-Col8.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Eremococcus.
OX NCBI_TaxID=908337 {ECO:0000313|EMBL:EFR30915.1, ECO:0000313|Proteomes:UP000005990};
RN [1] {ECO:0000313|EMBL:EFR30915.1, ECO:0000313|Proteomes:UP000005990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-139-V-Col8 {ECO:0000313|EMBL:EFR30915.1,
RC ECO:0000313|Proteomes:UP000005990};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. {ECO:0000256|ARBA:ARBA00007637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFR30915.1}.
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DR EMBL; AENN01000016; EFR30915.1; -; Genomic_DNA.
DR RefSeq; WP_006418701.1; NZ_AENN01000016.1.
DR AlphaFoldDB; E4KQB2; -.
DR STRING; 908337.HMPREF9257_1713; -.
DR eggNOG; COG0451; Bacteria.
DR OrthoDB; 9811743at2; -.
DR Proteomes; UP000005990; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd05272; TDH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42687; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR42687:SF1; L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:EFR30915.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005990}.
FT DOMAIN 4..241
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 324 AA; 36324 MW; 2741F046E90ADD7E CRC64;
MERILVTGAL GQIGSELVNK LCQDYGPENI VPTDLRYLEN NPICQHPNFR TLDVMDGDKF
LSLAQEFQVD TVMHLAALLS AVAEEKPQIA WSLNMGGLVN ALEVARQLNL QFFTPSSIGS
FGPSTPKDDT PQDTLQRPTT MYGVTKVSGE LLCDYYHHRF GVDTRGVRFP GLISYVTPPG
GGTTDYAVDI YYKAVIDGSY TSFIAPGTKM DMMYMPDALQ AIVDLMEAPE HQLSHRNAFN
ISAMSFEPEE IAASIRKYLP NFVMDYDVDP VRQAIADSWP NRLDYSAAET EWGFEAHYDL
DKMTQDMLAK LSQRFNLSDK FQLN
//
