ID E4N5K1_KITSK Unreviewed; 384 AA.
AC E4N5K1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative UDP-N-acetylglucosamine 2-epimerase {ECO:0000313|EMBL:BAJ26482.1};
DE EC=5.1.3.14 {ECO:0000313|EMBL:BAJ26482.1};
GN Name=mnaA2 {ECO:0000313|EMBL:BAJ26482.1};
GN OrderedLocusNames=KSE_06420 {ECO:0000313|EMBL:BAJ26482.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26482.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26482.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|RuleBase:RU003513}.
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DR EMBL; AP010968; BAJ26482.1; -; Genomic_DNA.
DR RefSeq; WP_014133801.1; NC_016109.1.
DR AlphaFoldDB; E4N5K1; -.
DR STRING; 452652.KSE_06420; -.
DR KEGG; ksk:KSE_06420; -.
DR PATRIC; fig|452652.3.peg.632; -.
DR eggNOG; COG0381; Bacteria.
DR HOGENOM; CLU_041674_0_1_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF3; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU003513, ECO:0000313|EMBL:BAJ26482.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT DOMAIN 38..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 384 AA; 39960 MW; F4F9149D9431A108 CRC64;
MAPPPPAPPA RDIAVVLGTR PEIIKLAPLI RLLGDRGRIV HTGQHYDSAL SGAFFANFGL
REPELRLDGA AGAGGRGDQI GTLTRDLARA FTAEPPRAVV VQGDTNSTSA GAQAAHYCGI
PVVHVEAGLR SGDRAMPEEI NRLVVGVLAD AHCAATAEAA ANLRATGTDG DRIRITGNTV
VEATLHSLPA PAERDRIVRE LGAPADFVLA TAHRPENTDR PDRLAALLGS LAELGELGHP
VLLPLHPRTR GRVKEFGMEH LLAGLTVVDP VDHPTFLALA DRAALLVSDS GGVQEEATVL
KKPLLVVRTS TERPEAVAAG FSRLVEPGAE LTAAARALLA DDGLAGRLRD TPSPYGDGRA
SERIRAIAVA LADGAPLPGD APGH
//
