ID E4N5N2_KITSK Unreviewed; 918 AA.
AC E4N5N2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Putative LuxR family transcriptional regulator {ECO:0000313|EMBL:BAJ26513.1};
GN OrderedLocusNames=KSE_06730 {ECO:0000313|EMBL:BAJ26513.1};
OS Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304
OS / NBRC 14216 / KM-6054) (Streptomyces setae).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=452652 {ECO:0000313|EMBL:BAJ26513.1, ECO:0000313|Proteomes:UP000007076};
RN [1] {ECO:0000313|EMBL:BAJ26513.1, ECO:0000313|Proteomes:UP000007076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 /
RC KM-6054 {ECO:0000313|Proteomes:UP000007076};
RX PubMed=21059706; DOI=10.1093/dnares/dsq026;
RA Ichikawa N., Oguchi A., Ikeda H., Ishikawa J., Kitani S., Watanabe Y.,
RA Nakamura S., Katano Y., Kishi E., Sasagawa M., Ankai A., Fukui S.,
RA Hashimoto Y., Kamata S., Otoguro M., Tanikawa S., Nihira T., Horinouchi S.,
RA Ohnishi Y., Hayakawa M., Kuzuyama T., Arisawa A., Nomoto F., Miura H.,
RA Takahashi Y., Fujita N.;
RT "Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
RT snapshot of the family Streptomycetaceae.";
RL DNA Res. 17:393-406(2010).
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DR EMBL; AP010968; BAJ26513.1; -; Genomic_DNA.
DR AlphaFoldDB; E4N5N2; -.
DR STRING; 452652.KSE_06730; -.
DR KEGG; ksk:KSE_06730; -.
DR PATRIC; fig|452652.3.peg.663; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG2197; Bacteria.
DR HOGENOM; CLU_006850_4_0_11; -.
DR Proteomes; UP000007076; Chromosome.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF14559; TPR_19; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007076}.
FT DOMAIN 852..917
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT COILED 756..783
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 918 AA; 97472 MW; 794460845DA07144 CRC64;
MPDSATWVSE LREPAVAVLP VVPDDLPGTR RVVLFGPPGI GKSTAAGLLA RRLGRPVLRL
APGPQDAGVP YTGLLELALA LPPSPTARDL AAALDEAADP AAAPDGTGPA LRLRRLTAAA
LRDAPPVTLV ADNAQWLDPA SRAVLRWALR LTPELPVITA ERTWRPGSGG HWSGEDAYAV
HVPHLTEPQL AALLAPYRPA PGEVARVHTR SGGNPALALA LAEAGGRTPG PPTVRRPADD
DPVLPPRARQ LVGEWLDTVP DDVRELLTLA ALDDRPDLDL LTRLAGPAAA HLLAQAETAG
LLDPVPADGR VRFTATAIAA ELTTRLPAAA RRLLHARLAG ASHDSLRRDR HTALAADPTD
PRTARHTARA AGHARLRGEH PLAAELSLLA AQRTPREDPG LLAERALTAV RDASHCGDLP
RGRAAARLVL EHDTSPAPRV GALLALLDAS GQRLHGADEL FADAIHEAAG RPDLTAQVLL
RQAIWANVSE GAPHRAAALA ERAARLARTA GDTTTTALAL TMLARVQRVL GHPDADTTLE
HALSLPRTAL VPVNATPEHL AARHALFDDR PADARTTLLP LLVQAQRTGD AEAVVDLLRS
LAETELRAGR CAEALDYARR AHTLSDRTGM PPGPACYTSA LVEGTASRTG TALAHARRGI
DASRHEDNRV FLSRNLFALG HLLLTAGRPK EALEPLQEVR ALETLQQVRD PSVLRWHADL
AEALLAAGRP DEAEELLTDT HRTATDLGRD SVLPALERAR ALLDAARGQY DTAARRLTDA
AEQLRQLPLE RGRTLLALSH TERRARRRAG ARTAAQRAAD LFTAHGAHPG ADAAARALRR
LEPGPPADAT PQDGARARLT DAEQRCAHLA AAGASNRDIA AALTVSVKTV EATLTRVYRK
LDLRSRVQLA HAVTPARE
//
