ID E4NQ81_HALBP Unreviewed; 407 AA.
AC E4NQ81;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=3-oxoacyl-(Acyl-carrier-protein) synthase II {ECO:0000313|EMBL:ADQ66643.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:ADQ66643.1};
DE SubName: Full=3-oxoacyl-ACP synthase {ECO:0000313|EMBL:ELY30750.1};
GN OrderedLocusNames=Hbor_10510 {ECO:0000313|EMBL:ADQ66643.1};
GN ORFNames=C499_02759 {ECO:0000313|EMBL:ELY30750.1};
OS Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 /
OS KCTC 4070 / PR3).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halogeometricum.
OX NCBI_TaxID=469382 {ECO:0000313|EMBL:ADQ66643.1, ECO:0000313|Proteomes:UP000006663};
RN [1] {ECO:0000313|EMBL:ADQ66643.1, ECO:0000313|Proteomes:UP000006663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700274 / DSM 11551 / JCM 10706 / KCTC 4070 / PR3
RC {ECO:0000313|Proteomes:UP000006663}, and PR 3
RC {ECO:0000313|EMBL:ADQ66643.1};
RX PubMed=21304651; DOI=10.4056/sigs.23264;
RA Malfatti S., Tindall B.J., Schneider S., Fahnrich R., Lapidus A.,
RA Labuttii K., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Anderson I.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Chain P.;
RT "Complete genome sequence of Halogeometricum borinquense type strain
RT (PR3).";
RL Stand. Genomic Sci. 1:150-159(2009).
RN [2] {ECO:0000313|EMBL:ELY30750.1, ECO:0000313|Proteomes:UP000011585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11551 {ECO:0000313|EMBL:ELY30750.1,
RC ECO:0000313|Proteomes:UP000011585};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467}.
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DR EMBL; CP001690; ADQ66643.1; -; Genomic_DNA.
DR EMBL; AOHT01000008; ELY30750.1; -; Genomic_DNA.
DR RefSeq; WP_006053867.1; NZ_AOHT01000008.1.
DR AlphaFoldDB; E4NQ81; -.
DR STRING; 469382.Hbor_10510; -.
DR GeneID; 9992870; -.
DR KEGG; hbo:Hbor_10510; -.
DR PATRIC; fig|469382.19.peg.548; -.
DR eggNOG; arCOG01278; Archaea.
DR HOGENOM; CLU_000022_69_2_2; -.
DR OrthoDB; 185488at2157; -.
DR Proteomes; UP000006663; Chromosome.
DR Proteomes; UP000011585; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:ADQ66643.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006663};
KW Transferase {ECO:0000313|EMBL:ADQ66643.1}.
FT DOMAIN 2..406
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 407 AA; 41283 MW; 3AE79A1F6FA22660 CRC64;
MERDVVVTGI GLVTALGETA DSTWAGLLDE RSGAGPITRF DPDEANVRAN VACEIGTDPA
ADTSDDRIDD RTMGRYTQFA VAAAAEALED AGFDPVDPAW TPERAGTSIG SGLAGLSEIE
AAAGSRPSPS FLVRALTNLA AGHVSMAVGA KGPNRAPGTA CSAGTHAIAA AADDIRRGRA
DVVIAGGTEA SISPLGVGSF DSMRALSTRA ADPAAASRPF DADRDGLVLA EGCGIVILES
RDHARERDAT PYAAVTGAGR SADAHHVTRP AESGDGLRRC IERALKDAGR DPAAVDHVNA
HATSTPIGDA REAEALNTVF SETDVPPTTS VKGHLGHALG AAGAIEAAIV AQTIAEGTIP
PTMNYETSDS DCDLPVVAEA RAMDVDVAVS TSAGFGGTNG ALVFEQP
//
