ID E4RPB9_HALHG Unreviewed; 412 AA.
AC E4RPB9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Diguanylate cyclase with PAS/PAC sensor {ECO:0000313|EMBL:ADQ13804.1};
GN OrderedLocusNames=Halsa_0329 {ECO:0000313|EMBL:ADQ13804.1};
OS Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus)).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=656519 {ECO:0000313|EMBL:ADQ13804.1, ECO:0000313|Proteomes:UP000007434};
RN [1] {ECO:0000313|EMBL:ADQ13804.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Begemann M.B., Mormile M.R., Wall J.D., Elias D.A., Woyke T.;
RT "Complete sequence of Halanaerobium sp. sapolanicus.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ13804.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RX PubMed=21602336; DOI=10.1128/JB.05209-11;
RA Brown S.D., Begemann M.B., Mormile M.R., Wall J.D., Han C.S., Goodwin L.A.,
RA Pitluck S., Land M.L., Hauser L.J., Elias D.A.;
RT "Complete Genome Sequence of the Haloalkaliphilic, Hydrogen Producing
RT Halanaerobium hydrogenoformans.";
RL J. Bacteriol. 193:3682-3683(2011).
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DR EMBL; CP002304; ADQ13804.1; -; Genomic_DNA.
DR RefSeq; WP_013404910.1; NC_014654.1.
DR AlphaFoldDB; E4RPB9; -.
DR STRING; 656519.Halsa_0329; -.
DR KEGG; has:Halsa_0329; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR HOGENOM; CLU_037495_0_0_9; -.
DR OrthoDB; 9798833at2; -.
DR Proteomes; UP000007434; Chromosome.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000007434}.
FT DOMAIN 10..57
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 199..252
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 281..412
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 412 AA; 48317 MW; F0EE1AEDB32CE382 CRC64;
MPWILVLSAK KILDSLIEGA FLFDKAKNII YLNKNAVRIT GYNLAELQKL EDFYELIKDP
AVKEDICCHL GQEDYYGIVS IRDKFASEKF VEIKFCFLEN RLYLITMVDI TFRIKKEAEL
KNIENKFRLA VKGAKIGVWE WEEQKGYSLL NPEDMNFFHF RAGFQKLDEK LLLKNIYFDD
RKRVAAEIDK IVNQNKDYLE VEYRVKSKNG DWKWIRNLAR VYERGEDNKA LKIIGIYLDI
DEQKKIERKI TELSLKDELT GLYNRRFFNE EIARLKNSRD YPITILVGDI DDLKQINDSC
GHNAGDDYIK LTAKILKNNL RAADIVARIG GDEFAVILPK TNWAIAEEIC ERIKNEYKQI
NHCSDSEKEF SISLGIATIN SSAEDIEDCF NRADKRMYKN KLQKKFNKRF DI
//
