ID E4RVG5_LEAB4 Unreviewed; 649 AA.
AC E4RVG5;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Aminopeptidase {ECO:0000313|EMBL:ADQ17029.1};
GN OrderedLocusNames=Lbys_1310 {ECO:0000313|EMBL:ADQ17029.1};
OS Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC
OS 106382 / 4M15).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Leadbetterella.
OX NCBI_TaxID=649349 {ECO:0000313|EMBL:ADQ17029.1, ECO:0000313|Proteomes:UP000007435};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Teshima H., Brettin T., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H.G., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Leadbetterella byssophila DSM 17132.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ17029.1, ECO:0000313|Proteomes:UP000007435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15
RC {ECO:0000313|Proteomes:UP000007435};
RX PubMed=21475582; DOI=10.4056/sigs.1413518;
RA Abt B., Teshima H., Lucas S., Lapidus A., Del Rio T.G., Nolan M., Tice H.,
RA Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA Pati A., Tapia R., Han C., Goodwin L., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M., Tindall B.J.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Leadbetterella byssophila type strain
RT (4M15).";
RL Stand. Genomic Sci. 4:2-12(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002305; ADQ17029.1; -; Genomic_DNA.
DR RefSeq; WP_013408078.1; NC_014655.1.
DR AlphaFoldDB; E4RVG5; -.
DR STRING; 649349.Lbys_1310; -.
DR KEGG; lby:Lbys_1310; -.
DR eggNOG; COG0308; Bacteria.
DR HOGENOM; CLU_015077_0_0_10; -.
DR OrthoDB; 9814383at2; -.
DR Proteomes; UP000007435; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09604; M1_APN_like; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR014782; Peptidase_M1_dom.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR Pfam; PF01433; Peptidase_M1; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:ADQ17029.1};
KW Hydrolase {ECO:0000313|EMBL:ADQ17029.1};
KW Protease {ECO:0000313|EMBL:ADQ17029.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007435};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..649
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003185852"
FT DOMAIN 372..550
FT /note="Peptidase M1 membrane alanine aminopeptidase"
FT /evidence="ECO:0000259|Pfam:PF01433"
SQ SEQUENCE 649 AA; 73525 MW; F160ADFA759B85A2 CRC64;
MKRLILALCF AWTGLYAQNY NSSEVFNPLN NYVPGNKYRS ASGQPGPEYW QNRADYQIKA
SLDTTLHQVK GQVSITYTNN SPDELTFIWL QLDQNKFKKD SRGNSVTPIS VGRYGVKGFD
GGYTLSEIKA EKPTGTAAPK GTVAKGKKSI LKDTYTEDTR LQIFLTEPLK KGEKVQISMQ
YEFLIPENGS DRMGMYKAQK GIIYQMAQWF PRVCVYDDIR GWNTSPYLGA GEFYLEYGDY
DFEITVPRDH IVVASGELLN PKEVLTSTQI SRLAEARKSD QTVFIVKEDE IGTSRPSGSG
NLTWKFSCKN TRDVAWSSSK AFVWDAAKIN LPSGKTALAQ SVYPAEVGSK DAWGRSTEYT
KFSIEFYSGW LMEYPYPNAI NVAGIVGGME YPGIVFCQAS SKKASLFGVT DHEFGHIWFP
MIVGSDERRY AWMDEGLNTY INSLAVKAFN NGEYFVPQAT SKMGRFLHPS KSILNTPDAI
PERELGILAY YKPSVGITML ADAIVGEERM KMALREYARR WAYKHPTPFD FFRTIENVLG
EDLEWFWRGW FIKGDKIDQA IKSVKYIKDK AENGAYIELE NVGALPMPVE LEIKEKGKDP
VIHKLPVEVW QKGSTWTFEH PSKAELEYVK LDPRGILPDV DDKNNTWKP
//
