ID E4RZE7_LEAB4 Unreviewed; 510 AA.
AC E4RZE7;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase {ECO:0000313|EMBL:ADQ16486.1};
GN OrderedLocusNames=Lbys_0725 {ECO:0000313|EMBL:ADQ16486.1};
OS Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC
OS 106382 / 4M15).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Leadbetterella.
OX NCBI_TaxID=649349 {ECO:0000313|EMBL:ADQ16486.1, ECO:0000313|Proteomes:UP000007435};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Teshima H., Brettin T., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H.G., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Leadbetterella byssophila DSM 17132.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ16486.1, ECO:0000313|Proteomes:UP000007435}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15
RC {ECO:0000313|Proteomes:UP000007435};
RX PubMed=21475582; DOI=10.4056/sigs.1413518;
RA Abt B., Teshima H., Lucas S., Lapidus A., Del Rio T.G., Nolan M., Tice H.,
RA Cheng J.F., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA Pati A., Tapia R., Han C., Goodwin L., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Goker M., Tindall B.J.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Leadbetterella byssophila type strain
RT (4M15).";
RL Stand. Genomic Sci. 4:2-12(2011).
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC NIT1/NIT2 family. {ECO:0000256|ARBA:ARBA00010613}.
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DR EMBL; CP002305; ADQ16486.1; -; Genomic_DNA.
DR RefSeq; WP_013407538.1; NC_014655.1.
DR AlphaFoldDB; E4RZE7; -.
DR KEGG; lby:Lbys_0725; -.
DR eggNOG; COG0388; Bacteria.
DR HOGENOM; CLU_519657_0_0_10; -.
DR OrthoDB; 9811121at2; -.
DR Proteomes; UP000007435; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR CDD; cd07574; nitrilase_Rim1_like; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR001110; UPF0012_CS.
DR PANTHER; PTHR23088:SF50; HYDROLASE YHCX; 1.
DR PANTHER; PTHR23088; NITRILASE-RELATED; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
DR PROSITE; PS51186; GNAT; 1.
DR PROSITE; PS01227; UPF0012; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007435}.
FT DOMAIN 4..204
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 220..475
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 510 AA; 59009 MW; FEB65703E69B28BB CRC64;
MEHIELEALT LEDYQELKAL MITTYDTVDD PYWEKYQIKR LIDIFPEGQV VIKVNKVLAG
CVLSIIIDED HFEEHHTYKQ VTGDYTFNTH NPHGTILYGI DIFIKKEFRG MRLGRRLYDY
RKELCEKLNL KSIIFGGRMP NYIQYQGKLT PRMYLEKVKN RDIFDPVLNF QMSNDFHPIR
VLKGYLEGDA ASNEYAVLMK WDNIYYEKPT LNIRTTKTIV KLGLVQWQMR PYKNLEELLQ
QVEFFVDALS SYRCDFALFP EFFNAPLMAA FNHLSESEAI RELSTYTDEI VQNFSRLSVK
YNIHIITGSM PELDEGVLLN VGYLCKRDGS LERFEKLHVT PDEAKIWGMK GGNILKTFDT
DCGKIGVLIC YDVEFPELPR MLAEDGLDIL FVPFLTDTQN GYSRVRNCAR ARAIENECYV
AIAGSVGNLP NVHNMDIQYA QSAVFTPCDF SFPTDGLKAE ATPNTEMILI VDVDLDLLKE
LHNHGAVKNL KDRRLDLYKL NRKSHLNKGD
//
