ID   E4T1P3_PALPW            Unreviewed;       497 AA.
AC   E4T1P3;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Peptidase M14 carboxypeptidase A {ECO:0000313|EMBL:ADQ78637.1};
GN   OrderedLocusNames=Palpr_0478 {ECO:0000313|EMBL:ADQ78637.1};
OS   Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Paludibacteraceae;
OC   Paludibacter.
OX   NCBI_TaxID=694427 {ECO:0000313|EMBL:ADQ78637.1, ECO:0000313|Proteomes:UP000008718};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=WB4;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Munk A.C., Brettin T., Detter J.C.,
RA   Han C., Tapia R., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Paludibacter propionicigenes DSM 17365.";
RL   Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADQ78637.1, ECO:0000313|Proteomes:UP000008718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17365 / JCM 13257 / WB4
RC   {ECO:0000313|Proteomes:UP000008718};
RX   PubMed=21475585; DOI=10.4056/sigs.1503846;
RA   Gronow S., Munk C., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA   Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Brambilla E., Rohde M., Goker M., Detter J.C., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Paludibacter propionicigenes type strain
RT   (WB4).";
RL   Stand. Genomic Sci. 4:36-44(2011).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M14 family.
CC       {ECO:0000256|ARBA:ARBA00005988}.
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DR   EMBL; CP002345; ADQ78637.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4T1P3; -.
DR   STRING; 694427.Palpr_0478; -.
DR   KEGG; ppn:Palpr_0478; -.
DR   eggNOG; COG2866; Bacteria.
DR   HOGENOM; CLU_029909_0_0_10; -.
DR   OrthoDB; 1111523at2; -.
DR   Proteomes; UP000008718; Chromosome.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR000834; Peptidase_M14.
DR   PANTHER; PTHR11705:SF91; CARBOXYPEPTIDASE A1 (PANCREATIC)-RELATED; 1.
DR   PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR   Pfam; PF00246; Peptidase_M14; 1.
DR   SMART; SM00631; Zn_pept; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Carboxypeptidase {ECO:0000313|EMBL:ADQ78637.1};
KW   Hydrolase {ECO:0000313|EMBL:ADQ78637.1};
KW   Protease {ECO:0000313|EMBL:ADQ78637.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008718}.
FT   DOMAIN          34..256
FT                   /note="Peptidase M14 carboxypeptidase A"
FT                   /evidence="ECO:0000259|SMART:SM00631"
SQ   SEQUENCE   497 AA;  56232 MW;  B2F0F9025BD7740C CRC64;
     MKKLLLLLLT IPMLVIGREL KTPLEKNNFS RPTTYAELSE YLKDLVAQNP KLALEVIGQT
     AENRNVYALK FSSSQFGKDP KKLKVLIFAQ QHGNEQSGKE GALLLAAELL KPENQYLFEH
     IDLALVPQVN PDGAEQNKRR NGHNADLNRN HLILEEPEAI ALHTFFDKYL FDVNMDVHEY
     APYFSEAWKK YGYRCNSDEL IGVNTNPNIP AEIRDFSNKV FVPFYHNYLT KKQYSSSIYA
     PGGPPEQDYI RHSTFDINDG RQSFGIQNSF SLIQEGLNGF DTFKDSLEHR AKGQETGMLA
     LLEFAARNHT QIKGMVASQR LNLIKGQPET VAIQMEHVKN GKQHPLPVYS YSTGKDSIIM
     VKDYRPVVKP ITSISKPEGY LIPKSSKLLL DWAKRHNFST STYKPSSKLK IEQYEVAAID
     SMDFEGDIIV NPRVKAVTIN SAIKASDYIY IPTAQLKGNM IVIALEPKSE LGLVTYTGYS
     QLLKANEKFP VLRVVKK
//