ID E4TVM5_MARTH Unreviewed; 442 AA.
AC E4TVM5;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=O-acetylhomoserine sulfhydrolase {ECO:0000313|EMBL:ADR21138.1};
DE EC=2.5.1.49 {ECO:0000313|EMBL:ADR21138.1};
GN OrderedLocusNames=Ftrac_1143 {ECO:0000313|EMBL:ADR21138.1};
OS Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408
OS / VKM B-1430 / H-43) (Microscilla tractuosa) (Flexibacter tractuosus).
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Marivirgaceae; Marivirga.
OX NCBI_TaxID=643867 {ECO:0000313|EMBL:ADR21138.1, ECO:0000313|Proteomes:UP000008720};
RN [1] {ECO:0000313|EMBL:ADR21138.1, ECO:0000313|Proteomes:UP000008720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 /
RC H-43 {ECO:0000313|Proteomes:UP000008720};
RX PubMed=21677852; DOI=10.4056/sigs.1623941;
RA Pagani I., Chertkov O., Lapidus A., Lucas S., Del Rio T.G., Tice H.,
RA Copeland A., Cheng J.F., Nolan M., Saunders E., Pitluck S., Held B.,
RA Goodwin L., Liolios K., Ovchinikova G., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Jeffries C.D., Detter J.C.,
RA Han C., Tapia R., Ngatchou-Djao O.D., Rohde M., Goker M., Spring S.,
RA Sikorski J., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Marivirga tractuosa type strain (H-43).";
RL Stand. Genomic Sci. 4:154-162(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
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DR EMBL; CP002349; ADR21138.1; -; Genomic_DNA.
DR RefSeq; WP_013453287.1; NC_014759.1.
DR AlphaFoldDB; E4TVM5; -.
DR STRING; 643867.Ftrac_1143; -.
DR KEGG; mtt:Ftrac_1143; -.
DR eggNOG; COG2873; Bacteria.
DR HOGENOM; CLU_018986_4_0_10; -.
DR OrthoDB; 634606at2; -.
DR Proteomes; UP000008720; Chromosome.
DR GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008720};
KW Transferase {ECO:0000313|EMBL:ADR21138.1}.
FT MOD_RES 209
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 442 AA; 48604 MW; DBF213B415AF20F1 CRC64;
MSTTQKFETL QLHAGQEIDP TTNSRAVPIY QTTSYAFNNS EHGANLFGLK EFGNIYSRIM
NPTNDVFEKR IAALEGGVAA VSVASGQAAQ FIALNNILEA GDNFISTKYL YGGTYNQFKV
SFKRLGIEVK FAPDEEVESY EALIDENTKA IYLETIGNPT FNIPDFEAIS ALAKKYDLPL
IVDNTFGAGG YLFRPIEHGA NIVVESATKW IGGHGTSVGG VITDAGNYNW GNGKFPQFSE
PSEGYHGLNF WETFGEGNPL GLPNIAYAIR ARVEGLRDFG PALSPFNSFL LLQGLETLSL
RVQRTVDNAL KLAYWLEKHP LVEKVNYPGL ESSKYYQLAK KYLHNGYGGV LSFTLKGDKE
ETKAFVDNLK LVSHLANVGD AKTLIIQPSA TTHQQLSDEE QLSAGISPNL LRVSVGIEHI
DDIIADFTQS FQKIHEESYA TA
//
