ID E4UA50_OCEP5 Unreviewed; 461 AA.
AC E4UA50;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=L-glutamine synthetase {ECO:0000313|EMBL:ADR37427.1};
DE EC=6.3.1.2 {ECO:0000313|EMBL:ADR37427.1};
GN OrderedLocusNames=Ocepr_1976 {ECO:0000313|EMBL:ADR37427.1};
OS Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 /
OS 506).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Oceanithermus.
OX NCBI_TaxID=670487 {ECO:0000313|EMBL:ADR37427.1, ECO:0000313|Proteomes:UP000008722};
RN [1] {ECO:0000313|Proteomes:UP000008722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14977 / NBRC 100410 / VKM B-2274 / 506
RC {ECO:0000313|Proteomes:UP000008722};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Zhang X., Brettin T.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Faehnrich R.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete sequence of chromosome of Oceanithermus profundus DSM
RT 14977.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADR37427.1, ECO:0000313|Proteomes:UP000008722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14977 / NBRC 100410 / VKM B-2274 / 506
RC {ECO:0000313|Proteomes:UP000008722};
RX PubMed=21677858; DOI=10.4056/sigs.1734292;
RA Pati A., Zhang X., Lapidus A., Nolan M., Lucas S., Del Rio T.G., Tice H.,
RA Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K., Hauser L.,
RA Jeffries C.D., Brambilla E.M., Rohl A., Mwirichia R., Rohde M.,
RA Tindall B.J., Sikorski J., Wirth R., Goker M., Woyke T., Detter J.C.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P., Land M.;
RT "Complete genome sequence of Oceanithermus profundus type strain (506).";
RL Stand. Genomic Sci. 4:210-220(2011).
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
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DR EMBL; CP002361; ADR37427.1; -; Genomic_DNA.
DR RefSeq; WP_013458597.1; NC_014761.1.
DR AlphaFoldDB; E4UA50; -.
DR STRING; 670487.Ocepr_1976; -.
DR KEGG; opr:Ocepr_1976; -.
DR eggNOG; COG0174; Bacteria.
DR HOGENOM; CLU_017290_0_3_0; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000008722; Chromosome.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF15; TYPE-1 GLUTAMINE SYNTHETASE 2; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:ADR37427.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008722}.
FT DOMAIN 20..118
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 126..461
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 461 AA; 51843 MW; C79A4F0809BEA984 CRC64;
MPHPRGKLTL DALAGLVAEG EIDTVVVAFP DLYGRLMGKR FDAEFFLEAA ARTGTHACDY
LLTVDMEMNP VPGYAFANWE RGYGDVHLVP DLDTLRPAPW HWTSNSAIVL ADVVSTETHE
PVPVAPRNLL KAQLARAAEA GFAVMAASEL EYYLYETPYR EFAERGFAAL RPAGWYLEDY
HVFQGSRTET FHFAARRDLR DAGIPVESTK GEWGRGQHEL NLRYTEALEM ADRHVLMKEA
LKEIADQQEM SVTFMAKPAG GQAGSSSHVH MSLWTGGQNA FAGERSIGRA QVSETFLHFL
GGLIRYAPDW MVFYAPTVNS YKRYEDASWA PTRLAWSYDN RTAGFRVVGA GGSLRVENRI
PGADVNPYLA YTAMLASGLA GIKEKLEPPP IFEGDVYAAA ELPRVPYSLR EAADLFEASE
LARRVLGEEV HRHYLHFFRT EWKAYEQAVT DWDRKRYFER I
//
