ID E4UP14_ARTGP Unreviewed; 357 AA.
AC E4UP14;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763};
DE Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};
GN ORFNames=MGYG_02780 {ECO:0000313|EMBL:EFQ99767.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028763}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase
CC subunit family. {ECO:0000256|ARBA:ARBA00011038,
CC ECO:0000256|PIRNR:PIRNR028763}.
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DR EMBL; DS989823; EFQ99767.1; -; Genomic_DNA.
DR RefSeq; XP_003175250.1; XM_003175202.1.
DR AlphaFoldDB; E4UP14; -.
DR STRING; 535722.E4UP14; -.
DR GeneID; 10030556; -.
DR VEuPathDB; FungiDB:MGYG_02780; -.
DR eggNOG; KOG3233; Eukaryota.
DR HOGENOM; CLU_033661_0_2_1; -.
DR InParanoid; E4UP14; -.
DR OMA; VGTTKKC; -.
DR OrthoDB; 930780at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR007832; RNA_pol_Rpc34.
DR InterPro; IPR016049; RNA_pol_Rpc34-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12780:SF1; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6; 1.
DR PANTHER; PTHR12780; RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED; 1.
DR Pfam; PF05158; RNA_pol_Rpc34; 1.
DR PIRSF; PIRSF028763; RNA_pol_Rpc34; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|PIRNR:PIRNR028763,
KW ECO:0000313|EMBL:EFQ99767.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|PIRNR:PIRNR028763};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR028763}.
FT REGION 202..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 39367 MW; 594A2DCC7292AD98 CRC64;
MASNAGPSRG KASSGDPQSL AMKLYDQCLS SFPADHLFYQ QDLLSLGVIP NDDLALLLRC
TQILVDQSML RLLQAKDDRL AWKIIAQSDA EKLQNLNGEE RLVYNVIHST GRNGIWTKII
KTRTNLHQTI MNRCLKTLEA KNYVKSVRNV KYPSRKIYML SGLQPSEEIT GGAWFTDGVL
DADFIRGLSG WIEHWVSARS WNSPGAEDQP KGKKRKAQAD DSETQYIPYL PSYQGHPTTA
DITKAINGSG LTPVTMDEGS ISQLLQMLCY DGRLVSLRDG AAYRSVKKPN EISLQRDLGL
QGPDGGAKES STLGSNGMTD APCGRCPVFS LCHPGGPVNA ENCEYFDEWL KSSTLSF
//
