ID E4UPL6_ARTGP Unreviewed; 395 AA.
AC E4UPL6;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=aristolochene synthase {ECO:0000256|ARBA:ARBA00039129};
DE EC=4.2.3.9 {ECO:0000256|ARBA:ARBA00039129};
GN ORFNames=MGYG_02903 {ECO:0000313|EMBL:EFQ99891.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Sesquiterpene biosynthesis; aristolochene biosynthesis;
CC aristolochene from farnesyl diphosphate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00037920}.
CC -!- SIMILARITY: Belongs to the terpene synthase family.
CC {ECO:0000256|ARBA:ARBA00006333}.
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DR EMBL; DS989823; EFQ99891.1; -; Genomic_DNA.
DR RefSeq; XP_003175374.1; XM_003175326.1.
DR AlphaFoldDB; E4UPL6; -.
DR STRING; 535722.E4UPL6; -.
DR GeneID; 10030682; -.
DR VEuPathDB; FungiDB:MGYG_02903; -.
DR eggNOG; ENOG502SDMI; Eukaryota.
DR HOGENOM; CLU_042538_3_2_1; -.
DR InParanoid; E4UPL6; -.
DR OMA; IFFWDDE; -.
DR OrthoDB; 2400051at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
SQ SEQUENCE 395 AA; 45459 MW; 0C14CA1535964573 CRC64;
MSFPAIFQWL VSAVTSPHSK IRGLSALLQA SSRNPKKDDY HRQQKNIINL LKGSSYTIPR
LEKCLEGWYM GVNPAYEKIK AGEGEFLREY VELMLHNLGD TNLTAFSIRR WIERDNLREM
AVKVDLSLCI ACFFPRTTEE KLQVLFEKMA WVYVDSFLTS EEFVRQDPAA FVKYWLDPNR
SGPEPYVLPS CIIYRTVGPK LAVGWSKESK AQFQKTTVEY IDCLMEVSKQ REKYLPSLEE
YIEGRIINIG VYPTLDLIPY AANIEVSDEV LRHESVQTIR WHIVRIICLM NDIFSVKKEI
KDCQFDNIIP LLLVHKGMSV QAAVDYTVGL IEESYRIVNA AGARLPKLDG KAKEDLDTYI
EQCKDQAAGS IYFHQYSPRY LPRSAFQGDK IVVQL
//
