ID E4UWB4_ARTGP Unreviewed; 509 AA.
AC E4UWB4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Ras-GEF domain-containing protein {ECO:0000259|Pfam:PF00617};
GN ORFNames=MGYG_05504 {ECO:0000313|EMBL:EFR02509.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989825; EFR02509.1; -; Genomic_DNA.
DR RefSeq; XP_003172920.1; XM_003172872.1.
DR AlphaFoldDB; E4UWB4; -.
DR STRING; 535722.E4UWB4; -.
DR GeneID; 10028196; -.
DR VEuPathDB; FungiDB:MGYG_05504; -.
DR eggNOG; ENOG502TBTA; Eukaryota.
DR HOGENOM; CLU_048480_0_0_1; -.
DR InParanoid; E4UWB4; -.
DR OMA; IPYLQEC; -.
DR OrthoDB; 2214318at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR Pfam; PF00617; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 352..485
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|Pfam:PF00617"
SQ SEQUENCE 509 AA; 58919 MW; EC90B922743E40DC CRC64;
MAYPRHMDSS LFIRQGSPLR HGNQPHSWHG RAIGSQRALS HPAIRLHQGR TDRSSSEPLP
STRPEPTFSF QLALPQFYVP YRWWEDGASM ILWAFDHQDI KRLLRFRLYE NDELPRHVLQ
NRNADVVSGF LASLLLTEQG LFSLELSHHD KVEEILGLCQ LRSVPVEPWR WHPNYSYNAE
PQTIASYIDV ESSRQFQAVP FEDWIRYALG YPTESIQWFF SQHKQLHDIV SAHLDLFPGE
FDTYVEVERH LRGGSPFAQY VLLQCLSVRG LLDSEVPDQS NQWVVGFIIR PIQELFKAHL
TGLPSMLKKL SVLALSFERK YRTSVEIDWS APFEANPAYL NDFFAFREVE PLARKLTHID
TREFSSLSVQ SFVEDTATLR LLSGRWHLLC SSTEECCLAL PEMATFFKSC ICVLHRLRNY
YSATAILYGL QKANINDFDL FLEQDDSPQQ YAINISSHCF KLMDSASNYA FYRETMKVRP
GIPFLLPHIV EYQSHGENAI VAMFPLCIH
//
