ID E4UX74_ARTGP Unreviewed; 1612 AA.
AC E4UX74;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=Sec7 domain-containing protein {ECO:0000313|EMBL:EFR02661.1};
GN ORFNames=MGYG_05658 {ECO:0000313|EMBL:EFR02661.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989825; EFR02661.1; -; Genomic_DNA.
DR RefSeq; XP_003173072.1; XM_003173024.1.
DR STRING; 535722.E4UX74; -.
DR GeneID; 10028349; -.
DR VEuPathDB; FungiDB:MGYG_05658; -.
DR eggNOG; KOG0929; Eukaryota.
DR HOGENOM; CLU_001772_0_0_1; -.
DR InParanoid; E4UX74; -.
DR OMA; FYTSIQK; -.
DR OrthoDB; 1369677at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041681; PH_9.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF373; PH AND SEC7 DOMAIN-CONTAINING PROTEIN C11E3.11C; 1.
DR Pfam; PF15410; PH_9; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 848..1012
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1008..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1181..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1453..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..250
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 615..650
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..731
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 810..859
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1031
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1054
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1453..1483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1612 AA; 178399 MW; 3EB5D3C01BD783C4 CRC64;
MPSSYRNPLS RASRHPDHRP QTPPQYRKET VSTRSRQLVR PSFPETFLDD FNPIDRHNNN
HGDVQDVDSV DEDERDPHDL SLNPALGVRS SVVDNMLLSL DQFSPSDAAD CSFDDSLPYD
SPHQQQESFS AYSSYHHHSD NNSNNHNNFS SSANSRIFSN RNNNSYNNDN SNGNDTSDNT
RFRSHTLSSS VSSDVEPYTH KGSHGQRHRH QNRHEADGRG YRSNSNPKKQ PTIRHVDGSS
EGERTTYRSK VYDSQRAISS NDRSQSRTTP RFVRRESTGS ASSSIDLNEM LATTSIYGTR
RSASFDYGST LPSRANGRDP SFGHRDTMMQ YDDMNAAPTP TVLLGPRKEF APPALSDHAS
TVHASTPPET SRTPSLAHKN STRSARSMYS RKNKSDTLGT STIRGRNDEY NKYFGESQDL
IPPVPALNQS SAPSPTIARS KQPLPATFPV ENVSTPPSKE RQGFFRRVFG SSKQSSPSQS
DVSPHSARDN ETDPSRYDNV SIHPRPYRPP PVPRDPSTAN NATRENPPVV TKKPSSFFRR
RKKSVVENVP PPLLPLSNLS STEVPKPESL ETEKLRISPA TDSLRTDSLS RAMKPYLSDM
DSPKHSPTHS SKPSSRGGKS RDQQETDESD IESPVKREKL RVKAPEIKSS KKLQKLGYLS
NPNSSRRAAG ASKTSPKSNS HSRATNFDGS FLADSSGNEG LSTKHSGNKN KQSRRPQTSP
DPPSQQYEHS TPRPKGELVL SDRVNGGKSQ SGDSNSNSLL EPTISPAHSK QASAPASPNS
TQSEHTSRQK QAGLHIDTSG KPLFATDKDK SPRISTSTSI TSNYHTAQST PVPSSDENLA
WGSTAMAPSQ GNLDTTDGGL HENTPCPEDR QQAQKIFDNN DEELAAGRYT AAWLGTPDRG
MLRKAYMDLF DWSDMNILSS LRSLCTKIAL KGEAQQVDRV LDAFSCRWCE CNPNHGFKAT
DVVHTISYSL LLLNTDLHLA DIEQKMTKPQ FIKNTMPTIQ RVVTEAAPEA FGTSQSSRPQ
TKQTAESEGS HPKNSPVPYL DKQFSHSPTT IERSDEPPTI DIPIIEHPSM PPPRLSSRAS
FLDTGHGLQS LAGPLVSTPF NGTMKAWEAQ VEMVLKDYYT SIHKQKLPLR GVTTESDEHI
PAHGGFLTLT HNMLRRTPST ISRAGAGDTY RGRGAENRLN AARWSSKARS RPRLYPPSAM
GSSRTSLDDQ SFVWSPSGSS TWSKNSLGKT LTSMSVDSLG SEYPRGDYQQ SIGFANALSH
AIIREDSAHS IAPSEDPARV AMVLEDEGLE LAGAPWAKEG SLKHKHHLDS IDKRAKDRNW
NETFAVIQRG WMRLFSFNSN NKSSRLKPKQ RQNGGLVVGG GNWMENADET WKFLLRHTIA
SALPAPGYSK SRPHVWALSL PTGAVHLFQV EFVSTANYWS ARLSKGPLFG AVSNIEYGWS
DAVINNAVSS LDDSNLPNSA PSSSSSAPLP RPSLQSSIRS SIDQGVRPRL PADRIVLSDW
RPPQQSMMAS TSSEAEQLET LRSYVKHVEQ ELQRHNELRP ALMLAFTPKH ANYSKALHNW
ERKSSYLLRE IVKFRTYIDS LVWAETQRER IYQADAAKEE ESNTGNPAPV ET
//
