ID   E4UX89_ARTGP            Unreviewed;       796 AA.
AC   E4UX89;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=ZZ type zinc finger domain-containing protein {ECO:0000313|EMBL:EFR02676.1};
GN   ORFNames=MGYG_05673 {ECO:0000313|EMBL:EFR02676.1};
OS   Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS   gypseum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX   NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN   [1] {ECO:0000313|Proteomes:UP000002669}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS989825; EFR02676.1; -; Genomic_DNA.
DR   RefSeq; XP_003173087.1; XM_003173039.1.
DR   AlphaFoldDB; E4UX89; -.
DR   STRING; 535722.E4UX89; -.
DR   GeneID; 10028364; -.
DR   VEuPathDB; FungiDB:MGYG_05673; -.
DR   eggNOG; KOG4351; Eukaryota.
DR   HOGENOM; CLU_007590_0_0_1; -.
DR   InParanoid; E4UX89; -.
DR   OMA; NKHGHHP; -.
DR   OrthoDB; 145583at2759; -.
DR   Proteomes; UP000002669; Unassembled WGS sequence.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd14947; NBR1_like; 1.
DR   CDD; cd02340; ZZ_NBR1_like; 2.
DR   Gene3D; 3.30.60.90; -; 3.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032350; N_BRCA1_central.
DR   InterPro; IPR000433; Znf_ZZ.
DR   InterPro; IPR043145; Znf_ZZ_sf.
DR   PANTHER; PTHR20930; OVARIAN CARCINOMA ANTIGEN CA125-RELATED; 1.
DR   PANTHER; PTHR20930:SF0; PROTEIN ILRUN; 1.
DR   Pfam; PF16158; N_BRCA1_IG; 1.
DR   Pfam; PF00569; ZZ; 2.
DR   SMART; SM00291; ZnF_ZZ; 3.
DR   SUPFAM; SSF57850; RING/U-box; 3.
DR   PROSITE; PS50135; ZF_ZZ_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00228}.
FT   DOMAIN          393..447
FT                   /note="ZZ-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50135"
FT   REGION          99..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          271..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          521..556
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          712..741
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..127
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..301
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        717..741
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   796 AA;  88330 MW;  200140CCBBF1CD8B CRC64;
     MPPAHNGPVK PDTLITVKAH FDGENRRFKV PLRDMGANTF PLRVRQFLNI PSHTEVIMRR
     YSDSAGAFLV LNAEHPAGYK QLYRAAKAKL KLRIQVDRVQ ELQPSNPPEQ LPEPEPEPEH
     EPKVTVEQQH QQQHYTPEPS KKLPEPITSP RSSYLDTVLD SRPAESPSAT RMLDSRTTIY
     PLPPVLPANT STATYSCSIM IDCNLCKAAI PNEHYHCSVC EDGDYDLCQE CIDAGNLCPA
     GTHWLIKRSL YDGQLVSSTT EIVGPKFFKP VELEPKPEPK AKQEPEPETY PESHPEPEPV
     PQEPKFPKLP EYAATDADYR PREPVVHRAL CDMCDYQIVD TRYKCIDCPN WDVCGNCVGD
     VKYAHPGHRF VPLYLPLPPR AAHNVVHPGV YCDGPLCHDK FNVNYITGIR YKCVVCDDTD
     FCETCEAHPN GTHNSTHPLL KFKTPVKHVT VTAYGEDETG QVFDRLGDRD APEPSFKSAA
     TETMPPLVTS TGAPIHPPMA LDAYEHDFEH GKEISYETQE VVEEEETPVV EPEPTVPKYE
     PVVSLPPAPA KDAKKVTAGG LHPDGLHTRF LSETIPDAQP FSPGTRIIKT WTLQNPGPCA
     WPAGTSAYFL GGDPMFDVDT SHAISLACLA NAMQSRPTTD PVYPGQEMEF TIPMKVPPRM
     GTAISYWRLK TSDGKAFGHK LSCHVEVIEP PPAPSPEKKS EMVFPTLEKE SPVASMHEYE
     SQPQSGEVIS DNVSDSASTL NEDAGVDVAD LAAEVNSLTL DIEHPDDESF LTDEEYDILD
     ASDEEYAEIA KASERK
//