ID E4UZC9_ARTGP Unreviewed; 473 AA.
AC E4UZC9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Association with the SNF1 complex (ASC) domain-containing protein {ECO:0000259|SMART:SM01010};
GN ORFNames=MGYG_06457 {ECO:0000313|EMBL:EFR03459.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the 5'-AMP-activated protein kinase beta subunit
CC family. {ECO:0000256|ARBA:ARBA00010926}.
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DR EMBL; DS989826; EFR03459.1; -; Genomic_DNA.
DR RefSeq; XP_003171913.1; XM_003171865.1.
DR AlphaFoldDB; E4UZC9; -.
DR STRING; 535722.E4UZC9; -.
DR GeneID; 10027172; -.
DR VEuPathDB; FungiDB:MGYG_06457; -.
DR eggNOG; KOG1616; Eukaryota.
DR HOGENOM; CLU_026512_0_0_1; -.
DR InParanoid; E4UZC9; -.
DR OMA; YYSASAH; -.
DR OrthoDB; 120305at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd02859; E_set_AMPKbeta_like_N; 1.
DR Gene3D; 6.20.250.60; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR032640; AMPK1_CBM.
DR InterPro; IPR006828; ASC_dom.
DR InterPro; IPR037256; ASC_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR10343; 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT; 1.
DR PANTHER; PTHR10343:SF84; ALICORN, ISOFORM A; 1.
DR Pfam; PF16561; AMPK1_CBM; 1.
DR Pfam; PF04739; AMPKBI; 1.
DR SMART; SM01010; AMPKBI; 1.
DR SUPFAM; SSF160219; AMPKBI-like; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 345..452
FT /note="Association with the SNF1 complex (ASC)"
FT /evidence="ECO:0000259|SMART:SM01010"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 51904 MW; D43F1F7A13BB907F CRC64;
MGNAPSKAPG ATAGVDKKVN RRTSIQALSS SKAPAADPSH SRESATGHHA ALKQQTPVHQ
RLQSRTVDTP IGSFGGERLE RRNSRKHREG DQYDLPVHSR GSQAVHAQQA VPVSDNVAAP
GEAFSTPRPV NIYYATPSNL TRPPRLPLPI GDAMTAPGSP ITSGSLGAAM AFDKANPEVS
PEKSELDPAI DEDDVVQDEL DSIVPTGFNK SVPTTIDWRG GGEKVYVTGT FVNWARKFKL
HKSDIESGMF TTVLQLRPGT HHLKFIVDGT MRTSDQLPTA VDFTNHLVNY IEISADEIER
PRRESDKPPK VIIPPEIFPP KVLPESLPID TTESQEESDK EEPEEEIPMG DFRNIIPQFL
VDIDRNEDDE GYHQAANVIR DSRAPPTLPL FLARSILNST TPMKDDNSVL NYPNHTVLNH
LATSSIKNGV LATSVTTRYK RKYVTTILYK PTGICSDVLG WVSAFLAPIR RLD
//
