ID E4V1D3_ARTGP Unreviewed; 857 AA.
AC E4V1D3;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Formin GTPase-binding domain-containing protein {ECO:0000259|SMART:SM01140};
GN ORFNames=MGYG_06848 {ECO:0000313|EMBL:EFR03848.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989827; EFR03848.1; -; Genomic_DNA.
DR RefSeq; XP_003170856.1; XM_003170808.1.
DR AlphaFoldDB; E4V1D3; -.
DR GeneID; 10026099; -.
DR VEuPathDB; FungiDB:MGYG_06848; -.
DR eggNOG; ENOG502RXE8; Eukaryota.
DR HOGENOM; CLU_008022_0_0_1; -.
DR InParanoid; E4V1D3; -.
DR OMA; WERCMGG; -.
DR OrthoDB; 2722688at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010473; GTPase-bd.
DR Pfam; PF06371; Drf_GBD; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 340..615
FT /note="Formin GTPase-binding"
FT /evidence="ECO:0000259|SMART:SM01140"
FT REGION 1..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 687..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..857
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 95288 MW; B6F4C60E9BA69705 CRC64;
MTPSIFSDSR PQSSKVSALR SILPSGGHKR SKSAFEAAVR GGPVHQSNPL AANCLLPADH
PHYRPQQQYQ QPYPDREANR NASNSRAPLQ DNSNPPGKAL HKRSKSTLSL KSLLKDKGTK
DKDKDKDQAL KEPVKQEAAP RRSKPKRTKS STSLSSLFRK HQSRQKDNDS GSRDKENFSP
TDIFDDAASI VPSVYTAHLP PDNGSGSRYV PENRRTVAEE MSLYTPQGYS PSKQRNFHDH
HQPSLTRSDK SRRKSESIPS TSAGVREMLA TGRKPSPLGP HNSNLPERKS SSSSNNSQAS
SKSNEALAKR RVSNGRRSSR VMAAIAAFNA KDQQSATPKQ NDPKATAIEN AFEQLLESRN
IPLNMRDKMR ALDTNIKADF VNKHEMTPTT PSGTSQKKFG FFSSDKEAEK GADSGSRKSA
TKTRARSRTF TKNDSSNSKK GKGETTPSKR PKSVDFSRPS SSSSRGISAT VLNSLQYIRT
PKETDEPSDF VHYLKEVQKP EIVEIAKLHK LRILLRNETV AWVTEFMSCG GMDELIQLLY
RIIKVEWREE HEDTLMHEVL LCLKALCTTT TALNHIRSIE SHLFPTLLNM LFDDEKKGPS
EFSTRGIIIS LLFTLLSNAG PGEQVSRAHT ILSYMRDPAP PETAQPLSFI ADIYQPRPYR
VWCKEVTNVT KEVFWMFLHH YNVVPATSSS EDGSVDPSQP YSERHFPPPH PPVPAAPYIG
GVEWEATSYL ANHLDLMNGI IASMPTAEER NRLRTDLKAS GFEKVMGRSL RTCKEQFYPA
LHAGLKVWVA AAAEDGWDYQ FVREGPPRDA PPSSPIKTAG NQSPKKRPGI VSEAPPRLDL
NVGVTSPDQR KSSGDWL
//
