ID E4V412_ARTGP Unreviewed; 319 AA.
AC E4V412;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Succinate/fumarate mitochondrial transporter {ECO:0000313|EMBL:EFR04736.1};
GN ORFNames=MGYG_07744 {ECO:0000313|EMBL:EFR04736.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; DS989828; EFR04736.1; -; Genomic_DNA.
DR RefSeq; XP_003170499.1; XM_003170451.1.
DR AlphaFoldDB; E4V412; -.
DR STRING; 535722.E4V412; -.
DR GeneID; 10025740; -.
DR VEuPathDB; FungiDB:MGYG_07744; -.
DR eggNOG; KOG0756; Eukaryota.
DR HOGENOM; CLU_015166_5_0_1; -.
DR InParanoid; E4V412; -.
DR OMA; YEWYKQL; -.
DR OrthoDB; 1386779at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR049563; TXTP-like.
DR PANTHER; PTHR45788; SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR45788:SF2; SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 11..101
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 113..204
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 215..304
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 319 AA; 34755 MW; 5CAEC1A9225CFEDD CRC64;
MASKDKKQQP ATAAVNLIAG GGAGMMEALV CHPLDTIKVR MQLSKRARAP GVKPRGFLAT
GQEIVRRETA LGLYKGLGAV LSGIIPKMAI RFTSYGYYKQ YLTNPETGNI SSSANMLAGL
AAGVTEAVAV VTPMEVIKIR LQAQSHSLAD PLDKPKYRSA PHALFTVIRE EGFGAIYRGV
SLTALRQGTN QAANFTAYSE LKKLLKDWQP QYNELPSYQT MCIGLISGAM GPFSNAPIDT
IKTRLQKTPG EPGQSAISRI TAISREMFKQ EGARAFYKGI TPRVMRVAPG QAVTFTVYEF
LREKLEKSNW AIMGGKYEE
//
