ID E4V5R2_ARTGP Unreviewed; 151 AA.
AC E4V5R2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=MGMT family protein {ECO:0000313|EMBL:EFR05437.1};
GN ORFNames=MGYG_08449 {ECO:0000313|EMBL:EFR05437.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989830; EFR05437.1; -; Genomic_DNA.
DR RefSeq; XP_003169544.1; XM_003169496.1.
DR AlphaFoldDB; E4V5R2; -.
DR STRING; 535722.E4V5R2; -.
DR GeneID; 10024774; -.
DR VEuPathDB; FungiDB:MGYG_08449; -.
DR eggNOG; KOG4062; Eukaryota.
DR HOGENOM; CLU_000445_52_5_1; -.
DR InParanoid; E4V5R2; -.
DR OMA; DEAEWWF; -.
DR OrthoDB; 2787022at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd06445; ATase; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR014048; MethylDNA_cys_MeTrfase_DNA-bd.
DR InterPro; IPR036217; MethylDNA_cys_MeTrfase_DNAb.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR42942; 6-O-METHYLGUANINE DNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR42942:SF1; ALKYLTRANSFERASE-LIKE PROTEIN 1; 1.
DR Pfam; PF01035; DNA_binding_1; 1.
DR SUPFAM; SSF46767; Methylated DNA-protein cysteine methyltransferase, C-terminal domain; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 12..97
FT /note="Methylated-DNA-[protein]-cysteine S-
FT methyltransferase DNA binding"
FT /evidence="ECO:0000259|Pfam:PF01035"
FT REGION 123..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 151 AA; 16720 MW; 93B377318EEE833F CRC64;
MARTDEAEWW FNAVYEAIQQ IPYGKVTSYG HIARLLGCPQ RSRQVGICLK HLPSSPDEYY
NNDNVPWQRV INSKGMISHR GPGSAARQAE ALQQEGVTVR SDSMNEFYVD MAQFGWFPDR
LPNEDEEEEE LGARSVGGGD LEGEVAAGGA G
//
