ID E4WW82_OIKDI Unreviewed; 524 AA.
AC E4WW82;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=GSOID_T00009149001 {ECO:0000313|EMBL:CBY21385.1},
GN GSOID_T00021600001 {ECO:0000313|EMBL:CBY33674.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY21385.1};
RN [1] {ECO:0000313|EMBL:CBY21385.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653017; CBY21385.1; -; Genomic_DNA.
DR EMBL; FN654436; CBY33674.1; -; Genomic_DNA.
DR AlphaFoldDB; E4WW82; -.
DR InParanoid; E4WW82; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR Proteomes; UP000011014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 169..299
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 524 AA; 60558 MW; 0F9B33ABF795979A CRC64;
MRFRNFQLPR GEQKTSDVYS FGIILQEMQY RQGPFFTGYD EMSITEKVQG LIDGNLYPWI
DDFENIALRQ QDLHKESNMR PPDFIVINKE LRKMTGKTKK NFGEILMVHY ESYLQNLDRQ
VRQREQEYKR QKFLADQVNS RLLPPGVVEQ LKNLGRNEKF DAKSYDEVSL YFSDIVGFTT
IGKQSTPQQI MTMMDKLFIM FDDIIGSFRC TKVETIGDAY FVVSGCPDEY EDHAAEIARF
ALAIRNCYVV DFQIPHLPQE RLRMRIGLHT GSVVASVVGN LMPRWCLFGE DLATVANCES
LGEANKIHLS SSIFAKLKDA KFADGRHMFE LGQDGVRKKS DMRFEISERS FEDEFQFKRV
TQVLGTTYFL VKDREKYETE VYNPSSVVER VTMLRQTKRD TNGHIRRVRR SSLHLESGSP
SGLAQDIQQV QKMTRFMATS SDTIDTAGIQ DISMVEDFSR LTQGNGGTRK GYRESITEMD
GMATKLKKRI TGRETIIYEG QEIGLRKRSM SNFELTNLDD LFEH
//
