ID   E4X2N5_OIKDI            Unreviewed;       479 AA.
AC   E4X2N5;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   22-FEB-2023, entry version 37.
DE   RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN   ORFNames=GSOID_T00017513001 {ECO:0000313|EMBL:CBY17888.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY17888.1};
RN   [1] {ECO:0000313|EMBL:CBY17888.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; FN653023; CBY17888.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4X2N5; -.
DR   InParanoid; E4X2N5; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd07623; BAR_SNX1_2; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR   PANTHER; PTHR10555; SORTING NEXIN; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          102..228
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   479 AA;  52943 MW;  25BB6637F25723B0 CRC64;
     MADLLGDDVF GDPNKVNAAP STDTSDVFAS AVSTQEVSTP VPVPVPVMTP APAVVTPAPA
     AVPKSPPKQS IDLFADESPA KSAAPAIQPS NGVSSATSGS VNDIKVIISD PRKAGDGIGA
     FMVFTVKTET SRSGWGGKVF EVNRRFSDFL GLYEKLAGRY QHKGYFIFPA PEKSISSFTK
     VKIGNEDDMF VQRRQQQLQR WINNIAKHAA LTRDIDFQGF LTQDTIAPAT STRALSAAGM
     LRFVGKVENV ITKQVTQKMP ETDSWFEDRA ASVDNLQAQL KRLSMASGNL SVHRRELGLS
     SGNLARASNM LANAEDKQDL SRRLANVGTI YENLGEIYTD LSDKDLYDFS ELLSDQVRGL
     DGIKNILEAR QKMWQNWQSS EQGLMKKRDT VTRLQATGRT EKIPGAELEI KEWETKAATS
     KKGFEDMTAV AKKEINTWET QRVAETKMFI LKWMKHMLEA EKKVVAMWEK YLPKAQNVK
//