ID E4X347_OIKDI Unreviewed; 683 AA.
AC E4X347;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00017685001 {ECO:0000313|EMBL:CBY18051.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY18051.1};
RN [1] {ECO:0000313|EMBL:CBY18051.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653023; CBY18051.1; -; Genomic_DNA.
DR AlphaFoldDB; E4X347; -.
DR InParanoid; E4X347; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR CDD; cd22211; HkD_SF; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR008636; Hook_C.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947:SF28; GIRDIN, ISOFORM A; 1.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR Pfam; PF05622; HOOK; 1.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT DOMAIN 8..147
FT /note="HOOK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19047"
FT DOMAIN 170..657
FT /note="Hook C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05622"
FT REGION 348..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 434..613
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 351..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 683 AA; 77623 MW; 836EC673FF9D298C CRC64;
MASNEGEEAL LAWVQSFSEI SVKRLVDLST CVELAHICTK VDSSFFNPEW KNNLSHTSLD
NKDLCKLNAI KVCERVLEYY KECLKLSFVN IDTPKSDEIA TGNIKEIACL IQFILGAAVN
CDNKNDFIGS LMTLDEYVQG ELMAYIQIIL DSCVSVGEES SNMDEEDLRQ RLFELEKELA
LSAEENQALR SDLESAKSFI SDGQNGKSNG EIDLIERRAV ETQRRLDEVQ EELMMMEHQR
EEESIRLEVA LRESEEWRQR TEIAEQKADE VAVLKDEVDY LREKADKSTR LQASLDSLRQ
KAEESNELRK KLRDAEDLAA QASREREEEL RKVKSYKTQL QSTKQALVEA QSKAVDDERR
SQRLENDLRA EKEMSKVSEA AAERVTAELI SLKTLNEELS LNSGNMDSLG ESLAAETAAG
DDMSLMPPQV REKMIRVQSE NKRLSEQVER EISRGRSDTV ELKDTIESLR CEKQTLTDKI
KDLEAKLAEG GVKEDGEAIQ ELEEKIKSVE SENASKKEQF NSISSELNAA KEKNGEVEAL
LKQKDEDIKA METRYRSYLE KARSVIKTLD PKNNNNTEVV ALRAQIAEKE RLIRRLETEK
AEKGKARDQE EKLLVSAWYN LGNKNIRGAV DERVGRSQPG QSFLARQRQQ TQQRRNQQRS
VQKARMNAAA GGAGDKKFFP SRS
//
