ID E4X394_OIKDI Unreviewed; 3553 AA.
AC E4X394;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE RecName: Full=G8 domain-containing protein {ECO:0000259|PROSITE:PS51484};
GN ORFNames=GSOID_T00017733001 {ECO:0000313|EMBL:CBY18098.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY18098.1};
RN [1] {ECO:0000313|EMBL:CBY18098.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653023; CBY18098.1; -; Genomic_DNA.
DR InParanoid; E4X394; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR CDD; cd00603; IPT_PCSR; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR019316; G8_domain.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR46769:SF2; FIBROCYSTIN-L; 1.
DR PANTHER; PTHR46769; POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1; 1.
DR Pfam; PF10162; G8; 2.
DR Pfam; PF01833; TIG; 4.
DR SMART; SM01225; G8; 2.
DR SMART; SM00429; IPT; 2.
DR SUPFAM; SSF81296; E set domains; 3.
DR PROSITE; PS51484; G8; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT DOMAIN 988..1121
FT /note="G8"
FT /evidence="ECO:0000259|PROSITE:PS51484"
FT DOMAIN 1866..2008
FT /note="G8"
FT /evidence="ECO:0000259|PROSITE:PS51484"
SQ SEQUENCE 3553 AA; 392243 MW; D7D0A6315B9E8282 CRC64;
MMLLLSLLLY GVLGKEKERI VRFAKNQLVQ DNKATIVIGG DFREYNPTSV QAKAGSKTFN
CQIKDKTDES VTCSLALRKD IENYRITLLS RNDEGLTELV CEKPRDCLVS RDGAPERTVD
FESTSRRFTP ESAPIITEVG PAEASYRGGT IFTIAGVNFG ESLESFGEEG RADNSDIHVF
FANGLTYIPC TMITHWYNPG EIACQAEPFG REAQWATLVY LNGEKLLANC GDCIVQTRSP
SSGQTVGFEI LHGNVAYPGP APAWTSWTSV SGTVDGQEII FLDTFYSHDF GCRAPIAFQA
KFTDGDILSE EDFEENFSTS QPSKIICPEV GCDGFEFKFL CDENSFFISL DGDRDNNDFA
AFDVDERENH LMAVEIETDF PTPGIVASCG LGYTDSDELH HLYSVYSKDR WSGAATCRVD
ARAIGDFTLS PIHLKAGRGV ADQDSLYMTE TGETANFGLA PRIDSITPAE GSRFGGTFIT
ITGKNLANNH QQTRVLLARN VPCTIISSSA TELICQVDRA EIDTSVQLFV KNIAASCEQC
DFTFVSGDSA TTLSTSSITL DGQSQSLTIS GSGLDSTSIV MFGETSCTAE TDFCTITSTS
SSSVTLSFTK LPWGTSSVYV VTNAGFVDFT PGLEVSVSSS LGVTVTVGEN GRNVNGGTLV
TISGGGFGLA KRTIRFGAVE AEEVERTIDD IIVRSPEQSG ARNNEVDIGV DGVDSSLTTY
VYDAAGDDID MDVSNLSVTG DTVLITFSRT LIRRTVTFYI DTTPFHTTEV TGETYELFIP
AMEPGSYNFR ALVEYWFEMG YWVDSVTPNA GSYGGGTSIT ITGSGFYEDD KIGTLCGEEL
INCEINADNT EAICQTPTIP DWKWENETTC VFDWYHYEPP QRNDWVYVYD NSTTAYINSI
QPNKGGTLGG TKITIIGNKF IPGETTVTID DVSCDIDFIS VAVIVCETNA HTYSTAHLVK
VTVPDGNAVF NHPDAAKFWY VDRWSSIFTW GCTELTNCTG KPVDGDIAVI PWNQTVLLDE
STPLLKVLLI QGGTLVWDRK DGIKLRAEYV LITDGGHFEI GNEHDPFCGT VDEPIGAEIE
MYGHHRSIRL PIYGAKCFIT REGTINMHGC PIDTTWTQLN ATAEAGDSSI YVRNPVTNPD
HPMKSWKSGD KIVIATTGGR LSLAQSEERY IDSISEDGRT IFLTEPLTHR HIYHFSEWDG
EVLEVAAEVA LLTRNIKFYG NVNDEWTKEL PPCDEEYEPQ EGAIQSCYQN KWGDEIGSDE
FGAHFLMHMI EWGKIAHIEA FHMGQAFQFA RYSFHFHRSG KQPNSYFRGN AVYNTFNRVL
TTHGIHEALV EWNVGYNAMG HNFFIEDGCE EDLIIQYNLA IKTKPSNSLL NSDQKATAFW
ITNPFNTIQH NRAAGGVQMG YWVNPFERAF PHRGKPPVYQ DTECPVYRSV KKWYNNTAHD
MGLYGFWVMT LQEGSSYRPS TVDCQSTWPP GEAIFERGIF WNCLRGAEFA LVGDNVWMKG
FIAANNILGG LSVKESSSGR YEGEYNQYGM GIKDSTVIGY IDKSVPELAL CTRFGIETPW
KPAGHMSIEG IKFHNFDEGD GHNCVAIDAC YSSYPFDCGR TSHFERVEFF NSPRKFAADW
EHETVLVDRD GSLTGKGMAG WSVVPTSGLY PDSMCEPAPE FSVEFPCSFC QGIEFMRYGM
NNIAPDSIIG FNMDVVNKYG SSVVPFRNKR STHGRGWMGL ILSGETHDMS WQKHEHITNI
TYRGTVYDMG QHKHTTIRHP FYQEVDDAVI AGNKIKGYAD SQGQNFDGQE VAALDTYMEP
LTYHIDPQTS DFSIMFAKTD AINSYYDVNY NFEVFKCFWP DCTPPTTPPP TTPPTDLVEC
EWEDVACWED GVIPISGANV TIPVDKHVTL NGNLDVDILF LEGTLTISDA QDVTINVRDI
LINTGAGGHE HLWSRSVYFQ NGNLFAGTPD APFNCDRTLT INFKGDRFQE EFGAPAGTVP
IGAKTIGAMG GLSLVGCPQN TPFSFLQTSV SAGATSITLT DDVSADWKAG DKIVVAASSY
DGRQYDELEI IAISGNTIAL NKALAFDHSG ADVGETFKTE VVHLTRNIKL DGKTDSEDMF
GGRIVVLSSD DGSSFRKGWA QLENIEMSHM GQFGHTRPDD LRTPVAFYHL GSQASADNPS
YIKGCSMYNS YNGGIAIGLG VTNMQVTDNV MFNIVSDAVR VVGDYSIVTG NVIVMVVNRF
MYQNWYLQQQ LGNAEAEQMN LPAGINTIEV KTGTLLNNRV AGGDGPAYKG HADECNMADL
CASKAWPMNI KNYAHSTLRG YSIIKKASRA CLRVEGFEFW RILDYGVYTQ AIGSSVQVIG
NKFVDTIIGV GHVMVGNGGP NGAHGSMKYS LDNNVFIGRS QHHTCSDYTV RAQAEIVTSG
LTGQNRAPLS PYNGHSGIMW PIFTESVTKF PKKPLHDPKE GTYPSPTGYS CSANNMFTDY
GDDSTCGRGS VIIQPNPKAL DITHSFDFSE TTLVNVDSDY ITKFKRPNLG DVNLADCVDL
TCDGMRKLLL KDMDGTLTGN GVETSIIAQS EYQWRDVPGF TWSNNVDDSF GLGDYRVPES
MLTNTDGTVI SIDDYAPHKG LSRGDSCTWD AKQLTYHCMG SSRAHLIFES LDMDQEERRV
APVAFRSSQG YIDLSNGPHD KSCCAGYSCS LRATMNHFVA ECGETYDFHC TGTTPTHIQF
AMYNVPSSCK IRIAMFTHRQ NRQDVFLNGN NMIYSNQYDF ATHNWKFPSP AFIPEVTHSS
GSNYFDRADQ ILYFTIGGGD MLRVKIANTI ILELDMMTEL TIEEFYSSPD LPYLLAALLG
LDPSQVKVVN VQRENWVRAQ STWSQQKTTV SKPHLKNSIN VRVSIEFGKP LGTVFGRSIG
EPDFAKIGSK LVQKQMDGDL EESIKSIAVS QGNDLDVVAT TLTGEPVAGD VSDWYEEDPL
GEGITILNDL GITEEEALAA ENVQEIVENK AAETGNQDLI AVTTVEKQAE KETIIARTTE
AKVYDGIPTS MKIKQEPGET VVNQRPKQGF KVVMLDQDGE EMTEVGYTGD PFRVSIYETN
GMFINAPETT FTPGSGVADF SGLRLPNTGS FQLTAYLTYS GTETNFTIPE VTSQSFQAVE
APPGFVQIEY IDNGTVYAQE PFPEISVQIF DTNDEYMAAC GPTGDECRVC VTSPTLEEGQ
LTGALTASYL SGRAVFNNIK STVDNSAVVL TFSLCYNQGA DTVLVGKDSS DPFVVRPNDE
PEPPVLDRCV GNNTYGEDLV FNSNLGQGMV LFKVLIGRGS ENFPYYDASY GNEIYHKEGD
KIRVACDQKG YVTGIKKLYS GFTCTCDGFN PCTFVQLNPD FVCISTEDAM LPVWAGGVFN
FVKKVMPSYV VLKGSVRNLL KLGEWEFDHI DESKHPDWVD PNFWQTADFT LFVWCPWNVT
LGGPDGSSGK IIFPDFYDGE HSDDGTLWTF YSREGTRLYK AKDPSKSSYF KGYADRSSDS
AFHGPITIDT SFQTSVDFTC ETGVLPGHQK NMLAKYTENF PIFEDGDFRK MVYYIRATHK
DLDDYIGYDL ERK
//
