ID   E4X9X2_OIKDI            Unreviewed;       407 AA.
AC   E4X9X2;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
GN   ORFNames=GSOID_T00004855001 {ECO:0000313|EMBL:CBY08292.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY08292.1};
RN   [1] {ECO:0000313|EMBL:CBY08292.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SIMILARITY: Belongs to the NHER family.
CC       {ECO:0000256|ARBA:ARBA00038110}.
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DR   EMBL; FN653031; CBY08292.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4X9X2; -.
DR   InParanoid; E4X9X2; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   CDD; cd00992; PDZ_signaling; 2.
DR   Gene3D; 2.30.42.10; -; 2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR14191:SF3; GH04176P; 1.
DR   PANTHER; PTHR14191; PDZ DOMAIN CONTAINING PROTEIN; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM00228; PDZ; 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
DR   PROSITE; PS50106; PDZ; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT   DOMAIN          147..228
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          281..364
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          383..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   407 AA;  45202 MW;  15481976A2E6DD3E CRC64;
     MEEDDVIVVA NGTKTEVLGH DEVIGVIQKN KNPVKLVLIN RKLNQAFKRL LINPADGDLI
     YELSLFKLKT EPTTSLPPPS YTPAVEDSDK LMTEEVIEEI VTREEAQVDE TQKDIVSEEQ
     SLLKNIKTRD SEREHRKKVV IAQRPRLVVL ERESPIEPIG FEYSSDNQNQ HFVNAIYEAS
     AADHGGLLTN DRILEINGEE VSGYNRDEID QLLKGENDTE LLVVDEATLI TLEERGIKIT
     AELARGINEP EAIKTSGASV SRAASTKLVP LPNTPQPLPR LVLLKKKNQT FGIEIGTEDD
     KFGNNSHRLI SIASSGPAAK TDAKIGDYLL EINEIPVAGK NHDDLKILIQ NSGKKMVLFL
     ADLECLDWHF DRQRAVDPDD AVQVPLAEFD SSDSETDASS IEKGPEF
//