ID E4XK83_OIKDI Unreviewed; 812 AA.
AC E4XK83;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Leucine-rich repeat-containing protein 51 {ECO:0000256|ARBA:ARBA00014223};
GN ORFNames=GSOID_T00013033001 {ECO:0000313|EMBL:CBY24860.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY24860.1};
RN [1] {ECO:0000313|EMBL:CBY24860.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN653063; CBY24860.1; -; Genomic_DNA.
DR AlphaFoldDB; E4XK83; -.
DR InParanoid; E4XK83; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06141; WRN_exo; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR46545; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51; 1.
DR PANTHER; PTHR46545:SF1; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 51; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT DOMAIN 76..256
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
SQ SEQUENCE 812 AA; 93138 MW; 7B9B6842A7FD9C6D CRC64;
MIQNQQFLRA LIGCALLKIW KVSRIDFCME KNLVAVTVAG LAYYFWNQHR KKEEKEETAE
RWFENITTGR IADSSITIAS SPGQVRRAIK EIYFYTRSYC NYVGLDCEWV GKNKTALMQI
SVSTPAGIKC FLIRLCKVDI RICYELMAFL RDEDVVKLGC GIDGDFKRLS EVDFVIFHPA
TISFFDLRQI IPATNYQNGG LANLTRQILG RKLNKDYRVR CSNWEADTLS NEQKTYAADD
AVCALQILGK LIQELGESRV QYFINEYKNT VFKQKSKPNK DKKEKSGKIT QNALEEKVKR
RLETRDYGSD YFNSATASVR KEPLYNNCVK LLAPDGEVLS ITDKKKADWY VKKGLGELVE
DTETSFIVRL KFEPSGRPNT DSEKYYVTEK ENVCVVCNEK NGLLRKNVVP REYRKHFPIV
MKCHVSHDVV LLCLRCHGRS NELDYLKRAR IADKFVAPLG NADLAKAILE PKERRNVRSG
GNALLKNRAK LPEKRINELE SIIMEYFNAT VWTGDLEQKA SDLPVLAGSE EEAQSFVQHG
EKVVASLMLS GGIESVKNFE VDWRQHFLDT MDPQFMPEGW NIYHNHERIE EKLDREIKRA
DGTFLKPCPP TEKNLDGIYI LLLNLKGMRE SRLSMITNRP ETSDPADFSF LFLSNMKDLQ
EVAPRESAHV KKRSDGKYNT ASIRLSNNII VELTGFSTAM ESIINNAFNA LQSVDLSFNE
IHKIDASFDH FPNIRSLYLH GNQINSLNEV KKLRSLTKLK RLTLHGNPID NLPNYRLFIL
YIIPTLQTFD FSGVSGDDHL LYFQMLNTTR NP
//
