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Database: UniProt
Entry: E4XNB0_OIKDI
LinkDB: E4XNB0_OIKDI
Original site: E4XNB0_OIKDI 
ID   E4XNB0_OIKDI            Unreviewed;       306 AA.
AC   E4XNB0;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   31-JUL-2019, entry version 32.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBY11348.1};
GN   ORFNames=GSOID_T00015665001 {ECO:0000313|EMBL:CBY11348.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY11348.1};
RN   [1] {ECO:0000313|EMBL:CBY11348.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M.,
RA   Cross I., Yadetie F., Muffato M., Louis A., Butcher S.,
RA   Tsagkogeorga G., Konrad A., Singh S., Jensen M.F., Cong E.H.,
RA   Eikeseth-Otteraa H., Noel B., Anthouard V., Porcel B.M.,
RA   Kachouri-Lafond R., Nishino A., Ugolini M., Chourrout P., Nishida H.,
RA   Aasland R., Huzurbazar S., Westhof E., Delsuc F., Lehrach H.,
RA   Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O.,
RA   Du Pasquier L., Boudinot P., Liberles D.A., Volff J.N., Philippe H.,
RA   Lenhard B., Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution
RT   of a pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; FN653082; CBY11348.1; -; Genomic_DNA.
DR   InParanoid; E4XNB0; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003276; K_chnl_inward-rec_Kir3.3.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF17; PTHR11767:SF17; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     54     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    133    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       31    162       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      169    304       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     25       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   306 AA;  35323 MW;  A32293A4FFE9B98A CRC64;
     MGLKLFDEPD QYGKTPNAKG MGKKPQVPRF MKKTGECNIR QDSKEKFERF ISDFFTTMID
     LPFSIFMLSY VSFYVFSWVI FSRYYWLVND TTYERPVCFE NVNSFKTAFL FFVETETTVG
     YGKRTITANC PEAILLLIIQ CLAGTMVDAF MVGCIFIKIS KPQNKNDTLI FSDNAVIAIR
     DGKYNFMFRI GNLRNSLFVK CICKVKFIKS KQTIEGEFLP LDQRDMDVGT ATGADKLFLV
     TPMVIKHEIN EKSPFWEMSC TDMMAEQFEI IVILEGVVES TGQSSQARTS YLNNEILWGH
     RYDNRL
//
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