ID E4XSK2_OIKDI Unreviewed; 548 AA.
AC E4XSK2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Beta-glucosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00002773001 {ECO:0000313|EMBL:CBY12714.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY12714.1};
RN [1] {ECO:0000313|EMBL:CBY12714.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
CC {ECO:0000256|RuleBase:RU003690}.
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DR EMBL; FN653136; CBY12714.1; -; Genomic_DNA.
DR AlphaFoldDB; E4XSK2; -.
DR InParanoid; E4XSK2; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001360; Glyco_hydro_1.
DR InterPro; IPR018120; Glyco_hydro_1_AS.
DR InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR Pfam; PF00232; Glyco_hydro_1; 1.
DR PRINTS; PR00131; GLHYDRLASE1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU004468};
KW Hydrolase {ECO:0000256|RuleBase:RU004468};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT REGION 19..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 407
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ SEQUENCE 548 AA; 62128 MW; F97E154DCFA0F7FB CRC64;
MKLLGSTILA AAFGGEVRPR PDDLTGSEAK CQPDAERDSF TAGKFPDNFK WSFATAAYQI
EGAWDADGKG KNIWDTFSQT DGNVQNNDTG NDACKSYYNM VRDVSNMKSL GVKDYRFSLS
WARLCPTGKC KDASGQEKRG IDHYHKFLDL LIEADIEPFV TLYHWDLPQN LETTYKGWEG
AQVVEDFGDY ARLVFSEYGH KVKNWITLNE AEVVCDLGYG IGVFAPGKAN LKSQFDCRHH
TVLAHTKAYH IYNDEFRATQ KGQIGITMNT DWYEGFNESK DNYDAAQRWM DLQLGFWADP
IYLTGDYPES VLKNNNDTIL QRFTAEQISQ NKGAADFFGL NHYTTRLVTD GNAAGENKGV
DYTQHTCPQW PQAGSEWLYS VPWGYKKLLT YIHNRYDSEQ YPIYVTENGV SSRGNGTDFE
PELDDQWRID HYTGYIGQMK RAIDEDKANV QVYTAWSLMD NFEWASGYTE RFGMVWVNFT
DPARPTYFKD SALFYSDLIT TNELQCSDGT NDGTCKAAPT TTTAQTTTTS SAQLVSFSAL
FFLIAQFF
//
