ID E4XWJ2_OIKDI Unreviewed; 1074 AA.
AC E4XWJ2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=E3 UFM1-protein ligase 1 {ECO:0000256|ARBA:ARBA00019780};
DE AltName: Full=E3 UFM1-protein transferase 1 {ECO:0000256|ARBA:ARBA00031516};
GN ORFNames=GSOID_T00007012001 {ECO:0000313|EMBL:CBY14047.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY14047.1};
RN [1] {ECO:0000313|EMBL:CBY14047.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the UFL1 family.
CC {ECO:0000256|ARBA:ARBA00010789}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN653245; CBY14047.1; -; Genomic_DNA.
DR AlphaFoldDB; E4XWJ2; -.
DR InParanoid; E4XWJ2; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0061666; F:UFM1 ligase activity; IEA:InterPro.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR InterPro; IPR034913; mS27/PTCD2.
DR InterPro; IPR018611; Ufl1.
DR PANTHER; PTHR31057; E3 UFM1-PROTEIN LIGASE 1; 1.
DR PANTHER; PTHR31057:SF0; E3 UFM1-PROTEIN LIGASE 1; 1.
DR Pfam; PF09743; E3_UFM1_ligase; 1.
DR Pfam; PF10037; MRP-S27; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 853..893
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..893
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1074 AA; 122966 MW; 09642B5AA860FFB8 CRC64;
MTLIRASRRC IALASLPKAS STAFEDFSKS FQLRLDYPVQ TTGDFIDQNL NKGEPVPSIL
LDQLIQTVET KKQFIDISYH LWRFRHSPFS YKMRPWTNYF LITKGVNLGA YEALVELLLK
SETYGCFPDS ASLCYLLLNL VENGENQLAV EACVDLIIKD LCGSQELAKL CLNIILSNLE
ILESCEAKQI YASIRIIGNL LKNEKLQDLG ACGISKSISD EDVTKDDHFY IDPYVNYEEL
CSNPEIDYET FIEQLQTAVD QNIFSNLENE LKEVLNDSVE TFKLWDAEAS DLHRALENLV
LDRKDWAERY KQLEKEFKAG VQYALSQTGL FNQRQAMEQR GSERMPKLYP PYMENEYFIV
AVSDLELEQD IYEAKNPEEW SKIKTFFENR KEEKEQALEE RRAPLRRSYK TNERWNGKMF
SEFDKPNSTP RLPIEMDEMW AEIEALQQQL AAAQEEDTSQ RLSDRNCIEI IMKLKEMNLV
ELIHSTNGKF YLTLSKLRSE VYDALVNAGG RSTIGDLADE VGVNYDHVEE ALAAIKDDKK
LVCYLGNFIT QEYLDFIAGE IYAMTNVTGF VSISKVSQDF DLSGEFLIEH VPKRCAAMIN
NQKTGFYTEA YIQRTTVTVR GYLSSAEKPL HMKHYYAKYK FADETIVDKV VDDMIKSKRL
KGKFLNRGQI ACFFPTIYLE EQTKAIKMRI ESYGYIKTDE LKHAIDTTNE KEAKRWMKEN
FPEFIQTDSH FMSHGFIERT KTELEQNVQQ IHLVDLFSIF PDALSEKDVE YIMRSASNSS
AIINDAKLFG ASWLMDDIAL EECAALFYPV VDERAEKAAS KKIVTIITED DFVKVDKKSL
SVKAEIIVAA GKEKGGAGGG RGAREVKTKG KNKKQKKKEA QEQTQKKETG GGALTEDEIK
DVLQQNEKYE IMEEDALQDL IDVIAPKLAK RYQTQATNIF TSKQQAQNDA KSARKMTRKE
QEQYINNCFC KLHLFHQGLE NLFGDPEQDT DSFIPQLRKY LHKTVGMDLV NAVFALSSDS
QETTLTAAMR QKILKGVEES DRVDMTAYDA LKALNDCKDV VEILGNHHST FFSD
//
