ID   E4XXM0_OIKDI            Unreviewed;      1820 AA.
AC   E4XXM0;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Dynein heavy chain tail domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=GSOID_T00007411001 {ECO:0000313|EMBL:CBY14414.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY14414.1};
RN   [1] {ECO:0000313|EMBL:CBY14414.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
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DR   EMBL; FN653283; CBY14414.1; -; Genomic_DNA.
DR   InParanoid; E4XXM0; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.10.287.2620; -; 1.
DR   Gene3D; 1.20.58.1120; -; 1.
DR   Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR   Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR042222; Dynein_2_N.
DR   InterPro; IPR013602; Dynein_heavy_linker.
DR   InterPro; IPR013594; Dynein_heavy_tail.
DR   InterPro; IPR042228; Dynein_linker_3.
DR   PANTHER; PTHR46532:SF13; DYNEIN CYTOPLASMIC 1 HEAVY CHAIN 1; 1.
DR   PANTHER; PTHR46532; MALE FERTILITY FACTOR KL5; 1.
DR   Pfam; PF08385; DHC_N1; 1.
DR   Pfam; PF08393; DHC_N2; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          220..780
FT                   /note="Dynein heavy chain tail"
FT                   /evidence="ECO:0000259|Pfam:PF08385"
FT   DOMAIN          1311..1478
FT                   /note="Dynein heavy chain linker"
FT                   /evidence="ECO:0000259|Pfam:PF08393"
FT   DOMAIN          1481..1688
FT                   /note="Dynein heavy chain linker"
FT                   /evidence="ECO:0000259|Pfam:PF08393"
FT   NON_TER         1820
FT                   /evidence="ECO:0000313|EMBL:CBY14414.1"
SQ   SEQUENCE   1820 AA;  209675 MW;  915DA7C4178B09C5 CRC64;
     MDGRHTHIFG LVAHALDKTE EQITDIAIAD ERWNLLDDFF KAGGSRKLMW YFQEPKIGEP
     GSANKSDTQS GVQKSTEPKL FLTTGREEML RGKCLLFMRL NKDKALTPRN MPDALFTQLD
     ASGKGGVLQA ISDYLRMVMM PHLRAQKSWG NLDAVGRAGQ TKINQFLESV DRFNQGLESA
     QKSIANAFKL EEVDIGYNLD VALEQEGVGS PIGNSDFATK LEQLMGVWCK QIELVLTESE
     QMRKEADDIG PSAELDHWKQ RMTKFNSLLT AISTRRVKLV YATLAENKSK LCPIWMDLDR
     RVSDVANEAR DNVKYLSTLD QYLGPLQTSD PMGMKDLLPN LINSIRMIHT ISRYYNTSER
     MTSLFVKVTN QMIKSCRAYI MQGSNGKVWD QEQDDLLERI DGCIDLKNEY QAQFAKAKDK
     LADEANRIPG GQDKHFDFSE NYIFGKLENF CHRLECIKKV IVTLRVLSKL KALRVDGIDS
     ILKNLEAFES NIKMRPGELD YKRADWDNGF KDFLASIGRL EADLQSFIKD WIEKPVPTTT
     VLEILAMFQP LSKDINLNMQ EAYQDMLRRY LKQDLVVARG AYNKQKSDPP GPKNFPPVAA
     RISWARQLFK RIDEPMTVIR PLQIEFKVLD TKDGKSCIKT YNQVGTALIE YETMYHQLWI
     GSVATARETL KGAILNRSGP DKEYEVNFNT DIYKLCKEGR FMKKIGLAIP PECEDLLISE
     ERLRQNHVNV NLLIEKFEST CQMVSSVMMP FLKFFITRME NALRPGSALL TWDSLNVPNF
     IQESGKVISE TRELFVAIND ILDCRIDAML KKIENTPMIE LPEEPVRAEK FISLTAATVA
     KAEEVFVQAS ANAESYVKEL VELLEKHYTK AEMDKLKHAA KTEHNPEWYY NLTAYFCARN
     TEAFVRCTRN SLDDLKRRLQ QSKVRYGSDE GGDGEKFPLF LADITLEIPQ VVFSPSLDDI
     QQTVNKIVDM VLSGGKKVVL WEHFELVKKH QAIEQDAARK RGEDKLKQIL EPKPFDRQLR
     EHKDVIKSVI PLNTIVSSLK TDAEMLLRGF STFQELWEID PAEKVRRFED EKPLYSDYGN
     QIRHYGILSG RISEIPESRT LGPIKFDTDL LNVSLTQECN NWKRAFGKAL DKKASGDMDK
     VFDIVEDQKK RLGREIKDLD DIRNSMGALR ELRENEVWIE MTIAPIEESY GILNRMDLVF
     NEGNQERVDT IGYAWKNTQA KAKSVQDSLA KIQGPFQENL ILSVEKFQRD TAEFYSDFDT
     QGPLVEGIKP SEASDKVTVF QGRFDELWRK YVTYSGGEEL FGMEVTDYPE LQRISKELNL
     LQKLYSLYNQ VLSSVDGYYE ILWSEMSIED INNQLLEFQA RCRKLPPALK TWDAYKELSK
     KIDDFNECCP LLEAMSNDAM LRRHWDRIEM VTKCKFPVEE DSFALRDVMD APLLENNEDI
     EDICISAGKE RDIESKLKQI IGEWENQDLT FSQFKTRGEL YNAPFKAKIQ EWNQKLSGSI
     EIIEQLLQVQ NLWVYLEAVF VGGDIAKQLP QEAKRFSNID KSWQKIMQKA HETTNVVKCC
     MGDDMYSQLL PHLLEQLEIC QKSLTGYLEA KRLLFPRFFF VSDPALLEIL GQASNCHTIQ
     DHLLSLFDNV KEVVFDTKVY EKVLAMRSQE GEEVDMVTPV ICTGNVETWL NTLMQTVHKT
     VHTIVRRAWQ NLGDSGFDLL RFEDTFCAQV GLLGIQLLWT RDAENALNEC RYDREIMKKT
     NDYFLELLNT LIDKTTQEMT KLDRVKFETL ITIHVHQRDI FNDMVQLKVR TPNDCEWQKQ
     CRFYYDENCD KCRISVTDVD
//