ID E4ZVR6_LEPMJ Unreviewed; 291 AA.
AC E4ZVR6;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=SH3 domain-containing protein {ECO:0000259|PROSITE:PS50002};
GN ORFNames=LEMA_P028440.1 {ECO:0000313|EMBL:CBX95692.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- FUNCTION: Plasma membrane osmosensor that activates the high osmolarity
CC glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
CC {ECO:0000256|ARBA:ARBA00003826}.
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DR EMBL; FP929127; CBX95692.1; -; Genomic_DNA.
DR RefSeq; XP_003839171.1; XM_003839123.1.
DR AlphaFoldDB; E4ZVR6; -.
DR STRING; 985895.E4ZVR6; -.
DR EnsemblFungi; CBX95692; CBX95692; LEMA_P028440.1.
DR GeneID; 13288332; -.
DR eggNOG; ENOG502QQC3; Eukaryota.
DR HOGENOM; CLU_956676_0_0_1; -.
DR InParanoid; E4ZVR6; -.
DR OrthoDB; 2906837at2759; -.
DR Proteomes; UP000002668; Genome.
DR CDD; cd11773; SH3_Sla1p_1; 1.
DR CDD; cd11774; SH3_Sla1p_2; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035800; Sla1_SH3_1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 92..159
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 160..217
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 232..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 291 AA; 31494 MW; 2E5121C883AB43C2 CRC64;
MYWIVSMTVI NVRRSGRRPT QPLPWPALSP LPLEVWPQAV ALRQAPVYPV YRRLLSSPAQ
AANRPQISLD APLPHTTGRC KGARPRPTAA MVFVGIYRAV YDYEPQSSNE LALKEGDILM
VLEKSTDDDW WKAKKKGGED EEHEPEGLIP NNYIEEAGPV AQAKALYDYA RQTDEELSFK
EDALLDVYDT SDPDWTLVGV ESDYGFAPAN YIELLQGSAE SAAAAAASPA LPSRPAMPAA
AAAAADSDDD QPPTPDSPPH QSPAAALAGI IQKKSGQSAP RPTISPPPNM T
//
