ID E4ZZ22_LEPMJ Unreviewed; 579 AA.
AC E4ZZ22;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Similar to uracil permease {ECO:0000313|EMBL:CBX96457.1};
GN ORFNames=LEMA_P107220.1 {ECO:0000313|EMBL:CBX96457.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; FP929129; CBX96457.1; -; Genomic_DNA.
DR RefSeq; XP_003839936.1; XM_003839888.1.
DR AlphaFoldDB; E4ZZ22; -.
DR STRING; 985895.E4ZZ22; -.
DR EnsemblFungi; CBX96457; CBX96457; LEMA_P107220.1.
DR GeneID; 13283241; -.
DR eggNOG; KOG2466; Eukaryota.
DR HOGENOM; CLU_021555_4_1_1; -.
DR InParanoid; E4ZZ22; -.
DR OMA; PDMYNFH; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR PANTHER; PTHR30618:SF0; PURINE-URACIL PERMEASE NCS1; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 62653 MW; 9EDD8C9F95BC9CC2 CRC64;
MALEDHKGGR ASERDSSSTD MGQSRPMKRT RWALAVEREP SSFAATPSAS NADFDPIPPS
KRTWATGSYI AYWMADAWAV SNWEVASSMI AAGLSWRMAI GACVLGNTIM GVIITVNGRI
GATLHVPFPV VSRMPFGYYF SYFVVVSRCA LAIIWLGVQT VTGGQCMAVL LAAIWPSFAR
IPNHVPESQG LSTSGFVAFL LYFLLQIPFL CIPYTKIQYF FGFKSIIAPI IFLAIFGDTL
RRAGGTIGNS TVITEGVTRH GSALSWAFFA NLNSVLGNYA TLGLNIADFS RYASKPSAQN
VQAIVIPCIF TVVGLLGIFT AAAAQSAYGH IIWNPIEILD LWQATGSSGG RAAAAFGAIG
LIIVTLGINI SANSISAAND LMAFCPKYIN IRRGQLLAAL IGAWACVPWK ILASAQKFLA
FLGGYTIFLG PMTAILMTDY YISRRGNVSV PDMYDFNGMY RYSARYATNW RSVVALVLGF
LPPLPGFINS VSLDTISLDS GAKNLFAIGY IYSFLAAGLF YWALMKFFPH LPSKLDHPVT
GEDVIVAADE KAIAAGERRV QRSMWEFLRG TRARGGGGV
//
