ID E5A0W9_LEPMJ Unreviewed; 576 AA.
AC E5A0W9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=LEMA_P103960.1 {ECO:0000313|EMBL:CBX97265.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; FP929131; CBX97265.1; -; Genomic_DNA.
DR RefSeq; XP_003840744.1; XM_003840696.1.
DR AlphaFoldDB; E5A0W9; -.
DR STRING; 985895.E5A0W9; -.
DR ESTHER; lepmc-e5a0w9; Fungal_carboxylesterase_lipase.
DR EnsemblFungi; CBX97265; CBX97265; LEMA_P103960.1.
DR GeneID; 13283836; -.
DR eggNOG; KOG4389; Eukaryota.
DR HOGENOM; CLU_006586_10_4_1; -.
DR InParanoid; E5A0W9; -.
DR OMA; NQMVGDY; -.
DR OrthoDB; 3085104at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 19..576
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005128120"
FT DOMAIN 30..505
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 576 AA; 62531 MW; B6F54E3273E4CE2F CRC64;
MKLLVFALLG AIAVATTAIP EVNANGVKYQ GIERNGVEIF LGIPYAQDTS GENRFKPPRP
HVFPPGATFN ATKPGHACPQ PLGVLFPPLG LGNITDISED CLNLNVARPK DMDAAKKLPV
MVWIHGGSFW WASNTEPTTA PDGLIRQSVE NGDPVIHVAM NYRLGFFGFA NSGTLKSEGS
ENAGLRDQRA AIEWVRDNIE AFGGDSENIT IFGQSSGGLA IGMHILAYGG TKPLPFQRGI
AQSQSLEPGI TGSFARDAMK AVVDYIGCNA TSLDEPETIS CLRKMDTAML LNASIITYQS
GIAHNIGDVW LPIVDGDFLP AGPSKLIAEG RFGNATFMSG WQQDDMNYYT NTSIITANDT
NEFIRAYLPA MPEASVAQLL NMYPVDEFKA SVNLTAEFHR SARIFRDILM VCPSLHLGEA
VEEKYHGPVF FFNFNQTILE PLLEHETNVS GYGVVHTSEF AYMFDSFRAY DVSGYPLHAA
QADRDLAVRA SRSWSTYASK GHAVAPSSPE HPSTTIQGWD GAFSCPGGPY VMTIGGPSEG
FFALTGVNST EVVRTQRLEE RCGFLNSRAI IEGLQY
//
