ID E5A2Y0_LEPMJ Unreviewed; 3089 AA.
AC E5A2Y0;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN ORFNames=LEMA_P094020.1 {ECO:0000313|EMBL:CBX97993.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
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DR EMBL; FP929133; CBX97993.1; -; Genomic_DNA.
DR RefSeq; XP_003841472.1; XM_003841424.1.
DR STRING; 985895.E5A2Y0; -.
DR EnsemblFungi; CBX97993; CBX97993; LEMA_P094020.1.
DR GeneID; 13285962; -.
DR eggNOG; ENOG502QUFK; Eukaryota.
DR HOGENOM; CLU_000211_1_0_1; -.
DR InParanoid; E5A2Y0; -.
DR OMA; DIMHTPM; -.
DR OrthoDB; 2787957at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR022099; DUF3638.
DR InterPro; IPR022105; DUF3645.
DR InterPro; IPR046541; DUF6606.
DR PANTHER; PTHR13367; UBIQUITIN THIOESTERASE; 1.
DR PANTHER; PTHR13367:SF28; UBIQUITIN THIOESTERASE ZRANB1; 1.
DR Pfam; PF12340; DUF3638; 1.
DR Pfam; PF12359; DUF3645; 1.
DR Pfam; PF20255; DUF6606; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 7..281
FT /note="DUF6606"
FT /evidence="ECO:0000259|Pfam:PF20255"
FT DOMAIN 1993..2216
FT /note="DUF3638"
FT /evidence="ECO:0000259|Pfam:PF12340"
FT DOMAIN 2335..2367
FT /note="DUF3645"
FT /evidence="ECO:0000259|Pfam:PF12359"
SQ SEQUENCE 3089 AA; 350644 MW; 5DA65BAF8FE4F8D8 CRC64;
MSVFIDVFNH LVLPPQLLGR QDESIGSTGD AIIARLIQAT LTLSRITSQE QTTPWYAISQ
SLHRYQSLHA HGRLEKLSLI CQFRKINQEQ PLLLHIAEQN AALIVRYNTS TQTEAVIFEA
FEISPSSTEV LASEGALICD FPDCSAQVPL AEFEKPSFQH ALAEFLEKGS MEPLRCFQAL
VTKAQTPIVE SRDTGSPGLV THLLIPLLES IGSSVDDDIP RLRKRVRDDA NIGVAEFPWR
RSPLWITLRV GIQRQLQITL GNESGRAYYK FLIVTLLIEL LLECPGRLAP ELTMTLRAKV
CRRLAKLEQE KSKSPELYGS LFITTAAFFK ESIIKVTHLV NLAWEKFRRD TTRSVPHLPT
RADQQSLFLS LPNSGSYLQN VLKLPRAQER TSPSLQLPPL HDTTVEQVEK FTDMYHGLTR
LESKIEKQEE PQLIGDRTLE SICEKLSEAI LGLMNTVGAA YNSDPEQMSI FILSLFRLWV
RLDKYMVKIS PLLLEYHPVF TPELLDALHI PTAAGMRRLR DIQNYIRNRC ERCIYQTTIF
SEPKEECFVV KYVSTSSSMQ QLHQRILVAT EASRQAKVSE LERWCSEYDE HCLGISGGIC
TCTFKRDGER DVRGCTKCWH WRVRNRMRIF AHEDFLPNDA IKAAAVIFEL AIPRSFAAYR
NATWKILMLA YPTKPQSGSP TVLLKDYGPL TAYASRNSTG ITIASTSKSF LGTHYKVSKK
KLRASESDVL YPNGLNFSYF DIGSGTWVKD FNKPLTFQHE CGVYVPLSLR SSVIQSSLHP
PTVTTGPSSY EIVASETQCP PSVSVHEFTA CQRLISGKTR RWLTMLVELG ASNVNFSSES
TMHLFNHLAI QAGPAKNKDD TFGDIHSVFD DMSFCDSLAA QVEKRLSDIT SNWREVHCME
VMITLTLRLC DLAVPMIRAD NLLVQARHIT LDWITRLRAD VRNAKETSIG ETAASYAFWA
ALLCRRTFSN ITESDTMMSE SDLSTFVQAS LALQENLLVD LAKLPPVLKR ILIRDTKITY
KIRKVLLRSI KAQPQSIGIA INASWSEPGS SARKLFDGWQ QVSPRHDRWV VSFMNNSKNP
ANTQVVHYNF IEGHLLVDGK PLGRLPHDVR ESDEVRQLFG DQRLLTFPSA EFGMSYVLAS
PICNHEIHFG SRNGQVVIRA WSQDELLEYI PSHRFVGPEA VDLPDGLISN CAHWLNLSTK
CLEIRRKPVL WRTRMNDWRV DLIKWQAHRS NRTLLVDPNS TLFKQVADIF RHFEDSRKIT
IFQPIHSKGN LSVELRHLEL AFFVNTKGLL QCRELNEEID PNQDAGTLYG LESKIVLRDI
ANIKRRSIIT PYEAISSARR GMHVTVRAAC STDYAKFGID DVLGRLSCPL EPRILYAKAQ
FHAYTSFVIP DPLTGRTGTE EALHMLQSAY CQPWQPLGRV AIDILKTIAD LSPKREYYPA
HKQALQAVSW NARLTVTIQH DAYEGLVQKI LDRSNYLEVF AQNAAKDVNI SAYVPSHLRK
RGLAQRRVYE RSVGDTIRPA ASDCMYKSRG QQPNSMQARK VYHIANLFQT KPFQINTSRE
LSAILQDWQL IGGFHTVRRA EVASLSDLVE KNVNEQWGSL VDICRHSDIN EPYSLMFRLS
LMSLNGTTDL DTIKILAAFA SLPTLRNLIP PSCSSFNQFK LNEKPSVKSI FRIISADLPE
KRHQINTRAE VEHRKACEAE GKRLAQHFLD QWPHEEVNLR GFDSDELDIG LAMERVIPEW
ERLHSNLALS EYVIRVQDVL RHHEGPGDMS YSKAWDWAQE QFHGETHDPV IPSILGDILP
KSLPGPLDRH ACELLLPNDI RISVGATQEI IATKPVKENV ELRQILCAFV KASNPLRQQY
GLDLKMSLDA LEKTSNQTLV QHTSPNITVN ARCIRDLRTV IATHLAQIQR ALSSNDDRFS
WLDLGNLWPC MTSISLLEQL RSRSSSKFGD FVQEAIVAHG ILITKLQRLV RIHNALYRGK
SNSLSEELGN SGHGNWNPLE WPDWLLLEID SDILIRQEQV DVAHAIIAPE SRNNTVLQLN
MGKGKTSCIV PMAMAVIGDG KQLPRLIVPK PLLLPTAQMI QSRLGGLVGR EIRHIPFYRR
TNISRRTLQL YRDLHQEILD VQGVVLIAPE HLLSYKLSGL QHLASANLET ACEMIEFQKY
LSSVCRDVLD ESDVSLAVKT QLIYPSGKQT TVDGHPHRWQ VAQSLLSLVK DHLPELEHKF
PRNIEVLQRG QGYPMIYILQ ADVEEDLHRH IVDEICTGRT SFLRFADCTT DSSIESLRRV
LLETSLDHEL LGRVAKLFTD DNIAFKTLLL VRGLLRNRIL LLCLRKRWNV QYGLHPKRDP
IAVPFEAKGI PSEQAEFGHP DAAILFTCLA FYYTGLSRVQ FREALRHILA SHDPASEYDR
WTSSCDSLPE ALHHWNVINS DDHDQVGELW RHLRADRTVL DHYMNHFVFP AHAKQFDIKL
QASGWDLPLF TRTEFDNPLT GARTTGFSGT NDNKMMLPLT IQQSDLPSLH QTNAEVLTYL
LQERNRAYHV VARGEKRLSE REFLEQLREK NIRVLIDAGA YILEMSNENL VKAWMDIDTR
PPAAVYFGAD NRAWVRYRGI KESVPLLATP FVDNMDNCLV YLDEAHTRGI DLKLPQDACG
ALTLALGQTK DHTVQAAMRL RQLPTTQSVC FFAFPETHQS ILDVCGMNET DRVNSSHVVT
WLLEQTCRSN EQLQNLYVSQ GADFCNRINA EWENADFLSN AKDRSAYVQV LQHPEQQTLE
ELYGSHKEHT HVPSSSTTKF TQLQTFKNKL NELRLNMSNT ATNLHSSALE EVEQEREVEF
QVEEVREVQK ALHHKAHVFP GLHPAISGFV STGRLCGVEG YEHVFDAVSR TSIGKRFDIS
GTESCLFVSA EFMKTIKTTM VDLIDNHLRP VEWILYNPTT FNALIIIAEE AEMVIPQIRN
QAFRSKVHLL TYSAPVTKKM VQFSSLRYYS LPALQSDYII PRSLTVELGI FAGRLYMQYD
ECAPLVDYID KASMNRRSNA RTNDTIRFIL EWVSLRRRGH DIMHTPLGYV CQGRPLGMEH
AFFVTNHASN NGVVNSYHNN GAVTGAQVD
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