ID E5A3X2_LEPMJ Unreviewed; 666 AA.
AC E5A3X2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Similar to CBS and PB1 domain containing protein {ECO:0000313|EMBL:CBX98317.1};
GN ORFNames=LEMA_P097260.1 {ECO:0000313|EMBL:CBX98317.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; FP929133; CBX98317.1; -; Genomic_DNA.
DR RefSeq; XP_003841796.1; XM_003841748.1.
DR AlphaFoldDB; E5A3X2; -.
DR STRING; 985895.E5A3X2; -.
DR EnsemblFungi; CBX98317; CBX98317; LEMA_P097260.1.
DR GeneID; 13286715; -.
DR eggNOG; ENOG502QVK2; Eukaryota.
DR HOGENOM; CLU_009026_1_0_1; -.
DR InParanoid; E5A3X2; -.
DR OMA; RERKQFF; -.
DR OrthoDB; 1328303at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR CDD; cd06409; PB1_MUG70; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF125; MEIOTICALLY UP-REGULATED GENE 70 PROTEIN; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 641..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 96..157
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 163..219
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 266..323
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 332..389
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 472..573
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..622
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 71982 MW; 0FBEA0333E6074F4 CRC64;
MSHTGTMRGT PKNRKPEPPH ITHSSPSGIP RPALETHASQ VTQSDAGTSL SASRAKMSKR
DDAIRRKIET DLNKKKSQSG RVRPSKKAPP GTVLALKPSP ALQIKPNTTV AEAAQLMAAK
REDCVLVTDE DDRIAGIFTA KDLAFRVVGA GIKARDVTIE EIMTKNPLCA KTDTSATDAL
DLMVRKGFRH LPVMDENHDI SGILDITKCF YDAMEKLERA YSSSRKLYDA LEGVQAEMGS
SQPQQIISYV EAIRQKMSGP TLESVLTGLP PTTVSVRTSV KEAAALMKEN HTTAVLVQDQ
GSITGIFTSK DVVLRVIAAG LDPATCSVVR VMTPHPDFAP MDMSIQSALR KMHDGHYLNL
PVMSDAGEIV GMVDVLKLTY ATLDQINNIS TTDNEGPAWN KFWLSMDDGT ESMMSGEGGS
RVHDHRSVMS HDNRPNLLDR GESVLPGDSA SHHGDSPSHS AVAGMPPTPL EDLPFPFKFK
APSGRVHRLQ VVASAGIEEL IQNVASKLGA EVDSIGGCPT FDGGKISKGG FALSYLDNEG
DTVSITTYDD LYEAISLSRQ AHREKVDLFV HDPEKPPMAA EVNPQPALAK PATPPDSVLR
QRKQFFDEEE EEEAKPRSRG RNQPVPRAEQ AEVIPGVPND LLLPGAIGVL AVVIVGVFIL
GRSTSR
//
