ID E5AB34_LEPMJ Unreviewed; 2024 AA.
AC E5AB34;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=THO complex subunit 2 {ECO:0000256|ARBA:ARBA00019596};
GN ORFNames=LEMA_P020050.1 {ECO:0000313|EMBL:CBY00875.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the THOC2 family.
CC {ECO:0000256|ARBA:ARBA00007857}.
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DR EMBL; FP929138; CBY00875.1; -; Genomic_DNA.
DR RefSeq; XP_003844354.1; XM_003844306.1.
DR STRING; 985895.E5AB34; -.
DR EnsemblFungi; CBY00875; CBY00875; LEMA_P020050.1.
DR GeneID; 13293018; -.
DR eggNOG; KOG1874; Eukaryota.
DR HOGENOM; CLU_000511_1_0_1; -.
DR InParanoid; E5AB34; -.
DR OMA; QERWTCI; -.
DR OrthoDB; 179356at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0000347; C:THO complex; IEA:InterPro.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR InterPro; IPR040007; Tho2.
DR InterPro; IPR021418; THO_THOC2_C.
DR InterPro; IPR021726; THO_THOC2_N.
DR InterPro; IPR032302; THOC2_N.
DR PANTHER; PTHR21597:SF0; THO COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR21597; THO2 PROTEIN; 1.
DR Pfam; PF11262; Tho2; 1.
DR Pfam; PF11732; Thoc2; 1.
DR Pfam; PF16134; THOC2_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668}.
FT DOMAIN 2..520
FT /note="THO complex subunit 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16134"
FT DOMAIN 522..597
FT /note="THO complex subunitTHOC2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11732"
FT DOMAIN 875..1187
FT /note="THO complex subunitTHOC2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11262"
FT REGION 226..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1218..2024
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1322..1336
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1341..1361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1370..1414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1429..1459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1628
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1655..1719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1739..1756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1791..1809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1853..1867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1878..1991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2001..2024
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2024 AA; 226290 MW; 709D498E3A84EFAC CRC64;
MLVKYGKFFV KFLRVSAWWP ELRGLDGIEW QEADVPTLPQ WALPSSPLWY YTDEEKETHL
RMREARDRKF WKRVGDLGDR MGIQAFFELG GRRITLNNRP AQLMPPVEGA PLTKQQAARM
WMDDWMEQTK TLPPSGNEIA AQLLGFKLRF YASDARDKSD TLPDNLIYLA ALLIKIGFIS
ILDLYPHLYP LEEDMPAHKE RLLQAKKERE QKEKGGVVNA LTMAGALPDD TLPPAVSRLR
ETESKSKPES ERSTPGRTDE GGDTKDVLPE PRDQKFQLLQ SLLCIGALPE ALFILGRHPW
LLEVHPELLD LIFRLAHHSL SKIYEDAKPE SGESTDPVTK GTGLRTTPRP SDYTPRRTLR
WAKPDQRDAG DGIDYKFYWE DWMDNVPVCQ EVGDVFKLCN TLLGLVGPEC GKDVVLLAKI
VRIGKRSLAE DSSDENRKRW IDFSAAFIAP ALSFTGKNPG IVNEVWDLLK QFDTATRYNI
YQQWFSGNKP AIRAAFAEVQ SRTKHELSRV SATNTKEYGR KLAKISYSSP GIVFKLTVKQ
LVAYPNMIDA LVECSRYLTL LGYDCLTWTL VNFFLNPDKG STQDDGMLSA PWLKNIASFV
GKAYQKYNLM DPVPVLQYTA SQLLRSEGEL FMLDVLEQMI KSMGGIAVSS SVSESMVLAL
CAGPVLRTYT LQHHLSDYRQ QAGSSARRLV KCLKDTGLAP QLLIALAQHV EAYPHRSDQQ
DTPDKVVLFN MDKLRSNLAQ YLELLRSYLS VNEFDSLFPP LIEMIADFGV EPDVAFTVAR
ASITAKANAF RAEQRANLLQ SKSMTSNDVV MEGTHDSAEQ HTTPPSGDVE MKDAKPSTSQ
DLTPSEGTLP DVPNAQIESL AEELKSSIPE TFAEHPCVSF YVTFWQLSLP DVDSNGMAQQ
YQKTVTAFER QLIATPIAEQ RRGGYKLNPP RKDADETRRI KLEIEKLKLE KATVSQASLN
TQLHLQNEMR HWFDGVPMLD SRSDALHNAL LQDCFLPRSR MSLQDAQFTA TMLNFMHKSG
TPGFRTIKLL DLLFTVNKLS CIISMYTEDE SRAFGRFLNG VLCELQIWHE NKNDAFARCA
QGEKKNLPGF GKRFDADRTA TDFLSYMEFC SLLYKWHKAL YTALKTCIDS GNWMQIRNSV
NVLKALHPVF PRVDFMATDL QHTITQLAEA DSRQDLKTSL LSILGDLNKS KKYWQTDHEF
RQVSTPDNLA HQACIDVSKM PAPPTPVNGH DKSVTEKAKP SSEASTPQLK PTAPAFKPRN
EVNGIHATPP ASKDDTTSKR PESTPATPAL PSRERESAMV LDDRVTAPSQ QEAGLPARTT
TKPGPPMHPS SVPPRPDGRN TPIHSASNTR ASHALPTRPD SQPPRNRQPE RPTTMDRPLE
HGTHHRYDTR APPNEYGRLE RPSEPVRQRE PSPGRRPRPV PGGRTPERMP GGADHREWSG
RDPRDYDDRA MRGHPRDTRA PPVRPPPGWD PRDTRDPRDQ RDRPDSRGHT APIPMEPRRM
PPTSSMAHEH VTARRDGPPP YRQGGERGDG PSITPRSSTP VAAASVGDGP TVDPARAALI
NQSEQHGLPE LSRQDRDSRR DRDSRPQSPR RGDDRRGDDR RGNERQMDDR PPAYHGRHDT
RDYRDERGLM QGPLPSGRDR RNDGSAITPT GPRVDRTEAS ASSRASREMF QPTQGSRPSG
QDPNYGRLNQ PSESMPPSGP RSDRPHGQSQ SSTPIAPTGP STPGGIHPSR LENIQGKGPS
GPPLQTNMSN APSGPRGSGR MPQGPMPPSP VGRGAPTGPA VNDRGPRNAT NPLRAINNVL
TQNTPADRSF ERNGPPASNP AVRGRGSTRA NGSIDAPGGM SSPMPPPSHN PMAISRPDSQ
QSRNSRLEPG PPHLEPTFQD EGRSDSRGHR ESRRSERSAH ERSTDRSDRR LDERGARNVP
VDRLGPPEED RGSDRDRREK SRIDRDSSRR DRERDGGERS GRESREPSRR ERVPREDGRT
SGGDGRDRRS RASASSAGGP EDVRKRTRDA TDQGMPHGDV KRRR
//
