ID   E5R3F0_ARTGP            Unreviewed;       377 AA.
AC   E5R3F0;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Oxidoreductase {ECO:0000313|EMBL:EFQ97965.1};
GN   ORFNames=MGYG_01001 {ECO:0000313|EMBL:EFQ97965.1};
OS   Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS   gypseum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX   NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN   [1] {ECO:0000313|Proteomes:UP000002669}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS989822; EFQ97965.1; -; Genomic_DNA.
DR   RefSeq; XP_003176917.1; XM_003176869.1.
DR   AlphaFoldDB; E5R3F0; -.
DR   STRING; 535722.E5R3F0; -.
DR   GeneID; 10032239; -.
DR   VEuPathDB; FungiDB:MGYG_01001; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   HOGENOM; CLU_026673_3_3_1; -.
DR   InParanoid; E5R3F0; -.
DR   OMA; SWLRRMP; -.
DR   OrthoDB; 2127369at2759; -.
DR   Proteomes; UP000002669; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08267; MDR1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF649; PEPTIDASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT   DOMAIN          25..369
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   377 AA;  40604 MW;  D1813F468A78435E CRC64;
     MASKITASIS IPRTMRAWVH HRTGSPSKVL SLKEDISIPT LPTDTSVLVR VSHVAFHPGI
     IILMHFVPSW LRRMPAVPET DFSGVIVSCG KNVPVSNGPR DFKPGTPVFG SLPVKPHLGT
     GQGALGEYIA IEAAAIARKP TNVSFAEASG LGVSAHTALV LVEAAEVSKD AKILINSPCG
     GVGHFATQLL RHRNPTARIT GICSGHNHAL ALQLGCTDTI DHTSFPNAEG QTLVQYLAAK
     HGSDEEKFDI IFDAYGSQDL WICSAKYLKP GKDHPYVTVG PKMGVSITEV PGFLWKMIMN
     STLPTWLGGV PRPYKQISAF TSTEAIERCK ELAQAGEFNT HFGEIWDMGE APGAYEVMGS
     GHARGKVVVK IWEPEEE
//