ID E5R3J1_ARTGP Unreviewed; 332 AA.
AC E5R3J1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MGYG_01806 {ECO:0000313|EMBL:EFQ98790.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the Cyclase 1 superfamily.
CC {ECO:0000256|ARBA:ARBA00007865}.
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DR EMBL; DS989822; EFQ98790.1; -; Genomic_DNA.
DR RefSeq; XP_003177742.1; XM_003177694.1.
DR AlphaFoldDB; E5R3J1; -.
DR STRING; 535722.E5R3J1; -.
DR GeneID; 10033077; -.
DR VEuPathDB; FungiDB:MGYG_01806; -.
DR eggNOG; ENOG502QTM1; Eukaryota.
DR HOGENOM; CLU_030671_1_0_1; -.
DR InParanoid; E5R3J1; -.
DR OMA; TGWWTRF; -.
DR OrthoDB; 2076300at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0004061; F:arylformamidase activity; IEA:InterPro.
DR GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:InterPro.
DR Gene3D; 3.50.30.50; Putative cyclase; 1.
DR InterPro; IPR007325; KFase/CYL.
DR InterPro; IPR037175; KFase_sf.
DR PANTHER; PTHR34861; -; 1.
DR PANTHER; PTHR34861:SF10; CYCLASE; 1.
DR Pfam; PF04199; Cyclase; 1.
DR SUPFAM; SSF102198; Putative cyclase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 37287 MW; 008A346BDDD0A02E CRC64;
MESGSKPSND LPWDPNNTKF PTRKNLPNIP GAPKGAAWVW GKDDNIGRLN LLTPTRVKAA
AAEIKTGEVI PLDLPFNVPE TPGFAREKFV HTIKTIVEGI AYDDLYELNT QFGTQWDGFR
HTKGEDIKGP NANHKCSIHH WAEHGITGRG VLLDYRSYAK ANGIDYDPYT PHAITYEELV
KCGKAQGIDI RPEAQGGDIK VGDILLIRSG WVESYHERSP EEREALALRP HSAGPGDGQK
YAGVAQEDDM LDWLHDCYFA AVAGDAPAFE RWPTPVSYYL HEYILALWGM PLGEMWDLER
LAKKCRETGR WFFFLTSAPF NVPVPPKQNQ YI
//
