ID E5RGF6_HUMAN Unreviewed; 72 AA.
AC E5RGF6;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=BRF2 RNA polymerase III transcription initiation factor subunit {ECO:0000313|Ensembl:ENSP00000430193.1};
GN Name=BRF2 {ECO:0000313|Ensembl:ENSP00000430193.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000430193.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000430193.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16421571; DOI=10.1038/nature04406;
RA Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA Platzer M., Shimizu N., Lander E.S.;
RT "DNA sequence and analysis of human chromosome 8.";
RL Nature 439:331-335(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000430193.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC130304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC138356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR ProteomicsDB; 15653; -.
DR Antibodypedia; 10831; 146 antibodies from 27 providers.
DR Ensembl; ENST00000521170.5; ENSP00000430193.1; ENSG00000104221.13.
DR Ensembl; ENST00000522539.1; ENSP00000429554.1; ENSG00000104221.13.
DR UCSC; uc064lyg.1; human.
DR HGNC; HGNC:17298; BRF2.
DR VEuPathDB; HostDB:ENSG00000104221; -.
DR GeneTree; ENSGT00390000002288; -.
DR HOGENOM; CLU_2721558_0_0_1; -.
DR ChiTaRS; BRF2; human.
DR Proteomes; UP000005640; Chromosome 8.
DR Bgee; ENSG00000104221; Expressed in skeletal muscle tissue of rectus abdominis and 206 other cell types or tissues.
DR Gene3D; 2.20.25.10; -; 1.
DR InterPro; IPR013137; Znf_TFIIB.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Proteomics identification {ECO:0007829|MaxQB:E5RGF6,
KW ECO:0007829|PeptideAtlas:E5RGF6};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00469};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00469}.
FT DOMAIN 2..36
FT /note="TFIIB-type"
FT /evidence="ECO:0000259|PROSITE:PS51134"
FT REGION 52..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 72 AA; 7894 MW; 9F3FDF602364BAA2 CRC64;
MPGRGRCPDC GSTELVEDSH YSQSQLVCSD CGCVVTEGVL TTTFSDEGNL REVTYSRSTG
ENEQVSRSQQ RE
//
