ID   E5SIS8_TRISP            Unreviewed;       506 AA.
AC   E5SIS8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   SubName: Full=Para-nitrobenzyl esterase {ECO:0000313|EMBL:KRY34866.1};
GN   Name=pnbA {ECO:0000313|EMBL:KRY34866.1};
GN   ORFNames=T01_373 {ECO:0000313|EMBL:KRY34866.1};
OS   Trichinella spiralis (Trichina worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichinellidae; Trichinella.
OX   NCBI_TaxID=6334 {ECO:0000313|EMBL:KRY34866.1, ECO:0000313|Proteomes:UP000054776};
RN   [1] {ECO:0000313|EMBL:KRY34866.1, ECO:0000313|Proteomes:UP000054776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISS3 {ECO:0000313|EMBL:KRY34866.1};
RA   Korhonen P.K., Edoardo P., Giuseppe L.R., Gasser R.B.;
RT   "Evolution of Trichinella species and genotypes.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRY34866.1}.
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DR   EMBL; JYDH01000060; KRY34866.1; -; Genomic_DNA.
DR   RefSeq; XP_003375158.1; XM_003375110.1.
DR   AlphaFoldDB; E5SIS8; -.
DR   ESTHER; 9bila-a0a0v0tws5; Neuroligin.
DR   EnsemblMetazoa; EFV55295; EFV55295; EFV55295.
DR   GeneID; 10905255; -.
DR   KEGG; tsp:Tsp_04344; -.
DR   CTD; 10905255; -.
DR   eggNOG; KOG1516; Eukaryota.
DR   HOGENOM; CLU_538998_0_0_1; -.
DR   OMA; RNITVEW; -.
DR   OrthoDB; 4386at2759; -.
DR   Proteomes; UP000054776; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR44590; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR44590:SF3; COESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00135; COesterase; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054776};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        468..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          46..185
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   DOMAIN          195..414
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   506 AA;  59115 MW;  9002111601FB9BD1 CRC64;
     MKFLFTFFEP AHHVFIWYSS TILGILFLIT VAQPTDQDHL NLVRRHTSYG DVLGFVHHGK
     LASAECYLGI PYARPPINDR RFAYPEPVDH WINLYNATYF RPWCVQFWYS DVYLEKREQS
     EDCLYLNIFV PRKTVHAKPY PVLVWIHGGS YQVGGSQLFP INGTVDNIVS HGVIFVSINY
     RLGPLVVDKY RENQSIIPLP AERLIRENAR LPLMIGSTTG ECIAYVSWLA YLAENDRIDL
     CNIEFVAPSF RFKNAEQVKQ AIYQHYFDNR PIQHDTNLSH ILVKIVTDQN IKVPMMKEIS
     YYTNKNVPIF VYSFDYSDDK LQNMHLSFAM RDQGAAHGFD LVYLFQSMSV LDPRNITVEW
     ASEDLNITYF IASTMTNFVK FGNPNFQKES NKLQFHWPPF DFPSSQQMYI GSQIKPIKVP
     FELLYFWNRT IEIIQTLSLQ HDFIFEPPTV SNFHCGVFED YELLNYRVAF FTVLTLSLAM
     LFLLGFCCFL HVNYRNQEKN IPTVVE
//