ID E5WD30_9BACI Unreviewed; 489 AA.
AC E5WD30;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|Pfam:PF13519};
GN ORFNames=HMPREF1013_00354 {ECO:0000313|EMBL:EFV79438.1};
OS Bacillus sp. 2_A_57_CT2.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=665959 {ECO:0000313|EMBL:EFV79438.1, ECO:0000313|Proteomes:UP000003283};
RN [1] {ECO:0000313|EMBL:EFV79438.1, ECO:0000313|Proteomes:UP000003283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_A_57_CT2 {ECO:0000313|EMBL:EFV79438.1,
RC ECO:0000313|Proteomes:UP000003283};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Larson L., Lui A., MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacillus sp. strain 2_A_57_CT2.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV79438.1}.
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DR EMBL; ACWD01000004; EFV79438.1; -; Genomic_DNA.
DR AlphaFoldDB; E5WD30; -.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_557420_0_0_9; -.
DR Proteomes; UP000003283; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR37947; BLL2462 PROTEIN; 1.
DR PANTHER; PTHR37947:SF2; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13519; VWA_2; 2.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003283};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..162
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13519"
FT DOMAIN 406..480
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13519"
SQ SEQUENCE 489 AA; 53877 MW; C311418BD9B2C3ED CRC64;
MGIEVKYPFL FLFLIPAVIM VFLFIRNHRG KGNEKFWIAS LRLVIFSLLI FALTVPQVLL
PVKGQTVVYL ADRSASIGSN DEALAWIENS ASKRKSEDQF AVAAFGKNVV LEQNLGRNRE
AITEFNGKAD DSQSNLEAGL QFAASLIPRD SSGRIVLMTD GNETAGKSLE AASVLKNRNI
EIDHVPLRTA AGDDVSISEL KMPPSLYLGE EAPITIEVTS NIAKEADIRL SVNHKEVLKE
SVQVNEGKNV YTFTHKADTA GLTVYKAEIA ADQDTFSENN TLHSVVNVKG TPKVLIVQGK
DAGDIANLLK GSGLETDTVL PEKLPTVLSG YLQYQSIIFN NVPATVISEH QMTLMEKAVK
EFGTGFIMFG GEESFGLGGY FKTPIEKLLP VDMDIKGKKE MPSLGLVLVM DRSGSMARNK
IELAKEAAVR SVELLREEDT LGFIAFDDRP WEILETEPLK DKKKAIEKIQ IYNSRRGDRN
LYFSGTSLQ
//
