ID E6K2S0_PARDN Unreviewed; 373 AA.
AC E6K2S0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Endonuclease/exonuclease/phosphatase family protein {ECO:0000313|EMBL:EFT82624.1};
GN ORFNames=HMPREF0620_1309 {ECO:0000313|EMBL:EFT82624.1};
OS Parascardovia denticolens DSM 10105 = JCM 12538.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Parascardovia.
OX NCBI_TaxID=864564 {ECO:0000313|EMBL:EFT82624.1, ECO:0000313|Proteomes:UP000004946};
RN [1] {ECO:0000313|EMBL:EFT82624.1, ECO:0000313|Proteomes:UP000004946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10105 {ECO:0000313|EMBL:EFT82624.1,
RC ECO:0000313|Proteomes:UP000004946};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFT82624.1}.
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DR EMBL; AEON01000002; EFT82624.1; -; Genomic_DNA.
DR AlphaFoldDB; E6K2S0; -.
DR KEGG; pdo:PSDT_0361; -.
DR PATRIC; fig|864564.6.peg.396; -.
DR eggNOG; COG3021; Bacteria.
DR HOGENOM; CLU_052333_1_1_11; -.
DR Proteomes; UP000004946; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:EFT82624.1};
KW Exonuclease {ECO:0000313|EMBL:EFT82624.1};
KW Hydrolase {ECO:0000313|EMBL:EFT82624.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Nuclease {ECO:0000313|EMBL:EFT82624.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004946};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 143..362
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF03372"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 40509 MW; E1C3E73AC3A891E4 CRC64;
MVSMVSMSQE NPSQNSKNTL RKHKSGKKRS PVIVWILLVL IAVWMSLHFL PTQYERYRPI
PDVTALISLL IVPLVILFFV AVSHRSFWQS LVSLILIAIN LVWSIGYVTP LPRQVSTIFS
MPAQNSAASP KQAAGQTASV TVMTLNGRYG RADASSIVHA VEQNHVDVLC MQEVTEDLVK
RLDQDGLTAR LPYSQLGESG ENDNGGFNAI WTRQAPVESH PASLPIASSN VPTATIFVGN
QPVLFASAHP MSPGRGGQAW QQSLSSLGAF GRLNNPLLAN RTQVTSQVVM GDLNSNLHHT
ALRDVLKAGL TDSGYQLHKG MNLSFPASWP LFPALIEIDH VLYAGGIHAT SLKTVAIPHT
DHKALIGTLA LEV
//
