ID E6K4X0_9BACT Unreviewed; 649 AA.
AC E6K4X0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Succinate dehydrogenase or fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:EFU31388.1};
DE EC=1.3.99.1 {ECO:0000313|EMBL:EFU31388.1};
GN Name=sdhA {ECO:0000313|EMBL:EFU31388.1};
GN ORFNames=HMPREF6485_0656 {ECO:0000313|EMBL:EFU31388.1};
OS Segatella buccae ATCC 33574.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=873513 {ECO:0000313|EMBL:EFU31388.1, ECO:0000313|Proteomes:UP000003112};
RN [1] {ECO:0000313|EMBL:EFU31388.1, ECO:0000313|Proteomes:UP000003112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33574 {ECO:0000313|EMBL:EFU31388.1,
RC ECO:0000313|Proteomes:UP000003112};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU31388.1}.
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DR EMBL; AEPD01000014; EFU31388.1; -; Genomic_DNA.
DR RefSeq; WP_004342081.1; NZ_GL586311.1.
DR AlphaFoldDB; E6K4X0; -.
DR STRING; 873513.HMPREF6485_0656; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_7_0_10; -.
DR Proteomes; UP000003112; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFU31388.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003112}.
FT DOMAIN 37..450
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 512..647
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 339
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 649 AA; 72597 MW; 572A878B06311DAC CRC64;
MTKTLNSRIP EGPVAEKWTN YKAHQRLVNP KNKLKLDVIV VGTGLAGASA AATLGEMGFN
VINLCIQDSP RRAHSIAAQG GINAAKNYQN DGDSIYRLFY DTVKGGDYRA REANVYRLAE
VSNNIIDQCV AQGVPFAREY GGMLANRSFG GAQVSRTFYA KGQTGQQLLL GAYSSLSRMV
QAGKVKLYTR YEMEDLVIVD GRARGIIAKN LVSGKLERFS ANAVVIATGG YGNTYFLSTN
AMGCNCTAAI QCYRKGAYMA NPSYVQIHPT CIPVHGDKQS KLTLMSESLR NDGRIWVPKK
LEDAKKLQAG ELQGKDIPEE DRDYYLERRY PAFGNLVPRD VASRAAKERC DKGYGVNNTG
LAVFLDFSES INRLGKAEIE ARYGNLFDMY EEITDVSPYE NPMMIFPAIH YTMGGIWVDY
ELMTTIPGLF AIGECNFSDH GANRLGASAL MQGLADGYFV LPYTIQNYLA DQEIWPRLST
DLPEFEEAEK AVDKEIDRLM GIQGKRSVDS IHKELGHIMW EHVGMGRTKE GLEEGLKMMA
ELRKEFDTNL FVPGTKDGLN VELDKAIHLR DFILMGELVA YDALHREESC GGHFREEHQT
EEGEAKRDDE HFFFVGCWEY QGDDTKAPEL IKEPLEYEAI KVQTRNYKN
//
