ID E6K826_9BACT Unreviewed; 517 AA.
AC E6K826;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=THUMP domain protein {ECO:0000313|EMBL:EFU30327.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:EFU30327.1};
GN ORFNames=HMPREF6485_1606 {ECO:0000313|EMBL:EFU30327.1};
OS Segatella buccae ATCC 33574.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=873513 {ECO:0000313|EMBL:EFU30327.1, ECO:0000313|Proteomes:UP000003112};
RN [1] {ECO:0000313|EMBL:EFU30327.1, ECO:0000313|Proteomes:UP000003112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33574 {ECO:0000313|EMBL:EFU30327.1,
RC ECO:0000313|Proteomes:UP000003112};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU30327.1}.
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DR EMBL; AEPD01000028; EFU30327.1; -; Genomic_DNA.
DR RefSeq; WP_004345683.1; NZ_GL586311.1.
DR AlphaFoldDB; E6K826; -.
DR STRING; 873513.HMPREF6485_1606; -.
DR GeneID; 82993804; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_2_0_10; -.
DR Proteomes; UP000003112; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EFU30327.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003112};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:EFU30327.1}.
FT DOMAIN 46..157
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
FT REGION 396..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 59837 MW; 6A853CBC6DBCDFAD CRC64;
MEQEFKLIAK TFMGLEPVLA QELIQLGANN VETGRRMVSF TGDKEMMYRA NFQLHTAIRI
LKPIHTFKAR SAEEVYDEIQ KIEWSNYLDN KKTFSVDSVV YSEEFRNSRF VTYKVKDAIV
DWFREKTGTR PNISVSNPDI RLNIHIAEDD ATLSLDSSGE SLHRRGYRQE SVEAPLNEVL
AAGMILMTGW KGDTDFIDPM CGSGTIAIEA ALIARNISPG VFRKEFAFEK WADFDQELFD
TIYNDDSKEK EFTHHIYGYD IDMKAVNTAR INVKAAGLSK EVTIEQADFK DFQTPTEKSI
MVTNPPYGER ISTPNLLATY KMIGERLKHT FAGNDAWILS YREECFEQIG LKPSIKIPVF
NGSLECEFRK YALFDGRMKE FRADGGIVKT DAEKREMAQK HRFKKEREFK KRLDEQEANE
EGDIRSFSFH KHDIGDLGFR KERTGRNDGD ERRTGRNERG GKRFGRGDRE ERGFGRFDRS
KRDERGGKRF ERGSKRFDRS DKRGGLGKKN RRFDDED
//
