ID E6KVS2_9PAST Unreviewed; 414 AA.
AC E6KVS2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN Name=tnaB {ECO:0000313|EMBL:EFU68381.1};
GN ORFNames=HMPREF9064_0254 {ECO:0000313|EMBL:EFU68381.1};
OS Aggregatibacter segnis ATCC 33393.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Aggregatibacter.
OX NCBI_TaxID=888057 {ECO:0000313|EMBL:EFU68381.1, ECO:0000313|Proteomes:UP000032871};
RN [1] {ECO:0000313|EMBL:EFU68381.1, ECO:0000313|Proteomes:UP000032871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33393 {ECO:0000313|EMBL:EFU68381.1,
RC ECO:0000313|Proteomes:UP000032871};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU367149}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|ARBA:ARBA00005452,
CC ECO:0000256|RuleBase:RU367149}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU68381.1}.
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DR EMBL; AEPS01000002; EFU68381.1; -; Genomic_DNA.
DR RefSeq; WP_006716841.1; NZ_LS483443.1.
DR AlphaFoldDB; E6KVS2; -.
DR STRING; 739.GCA_001059425_00172; -.
DR GeneID; 60799659; -.
DR HOGENOM; CLU_038102_2_1_6; -.
DR OrthoDB; 18749at2; -.
DR Proteomes; UP000032871; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR018227; Amino_acid_transport_2.
DR InterPro; IPR013061; Trp/try_permease_CS.
DR InterPro; IPR013059; Trp_tyr_transpt.
DR NCBIfam; TIGR00837; araaP; 1.
DR PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR PANTHER; PTHR46997:SF1; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR Pfam; PF03222; Trp_Tyr_perm; 1.
DR PRINTS; PR00166; AROAAPRMEASE.
DR PROSITE; PS00594; AROMATIC_AA_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|RuleBase:RU367149};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW ECO:0000256|RuleBase:RU367149};
KW Cell membrane {ECO:0000256|RuleBase:RU367149};
KW Membrane {ECO:0000256|RuleBase:RU367149};
KW Reference proteome {ECO:0000313|Proteomes:UP000032871};
KW Transmembrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367149};
KW Transport {ECO:0000256|RuleBase:RU367149}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 33..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 82..103
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 150..169
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 189..206
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 227..245
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 280..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 325..341
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 347..366
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 387..410
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
SQ SEQUENCE 414 AA; 44813 MW; 3C157AAD5B3580E5 CRC64;
MTIQKRPSLL GGAMIIAGTA IGAGMLANPT STAGVWFFGS IAILIYTWFC MTTSGLMILE
ANLHYPTGAS FDTIVTDLLG KGWNVINGLS VAFVLYILTY AYITSGGSIT ENFLNQLGEN
VEVGRTAGSL IFCFVLAAFV WFSTKAVDRF STVLIAGMII SFFLSTSGLL SSVKADVLLN
TVAQGEQQYL PYILTALPVC LVSFGFHGNV PSLVKYYDRD GKRVMKSIFL GTGLALIIYI
LWQLAVQGNL PRAEFAPVIA KGGDVAALLE ALNKYIQTDY IGIILNFFAY MAIASSFLGV
TLGLFDYIAD LCKFDDSRLG RTKTTLVTFL PPLLLSLQFP FGFVVAIGYA GLAATIWAAI
VPALLAKASR KKFPNATYRV HGGNFMVYFV ILFGLLNIFA QVALQFGWIA DFKG
//
