ID E6KXT5_9PAST Unreviewed; 598 AA.
AC E6KXT5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Oxaloacetate decarboxylase {ECO:0000313|EMBL:EFU67648.1};
DE EC=4.1.1.3 {ECO:0000313|EMBL:EFU67648.1};
GN Name=oadA {ECO:0000313|EMBL:EFU67648.1};
GN ORFNames=HMPREF9064_0967 {ECO:0000313|EMBL:EFU67648.1};
OS Aggregatibacter segnis ATCC 33393.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Aggregatibacter.
OX NCBI_TaxID=888057 {ECO:0000313|EMBL:EFU67648.1, ECO:0000313|Proteomes:UP000032871};
RN [1] {ECO:0000313|EMBL:EFU67648.1, ECO:0000313|Proteomes:UP000032871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33393 {ECO:0000313|EMBL:EFU67648.1,
RC ECO:0000313|Proteomes:UP000032871};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU67648.1}.
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DR EMBL; AEPS01000005; EFU67648.1; -; Genomic_DNA.
DR RefSeq; WP_006718285.1; NZ_LS483443.1.
DR AlphaFoldDB; E6KXT5; -.
DR STRING; 739.GCA_001059425_00584; -.
DR GeneID; 60800361; -.
DR HOGENOM; CLU_000395_4_3_6; -.
DR OrthoDB; 9760256at2; -.
DR Proteomes; UP000032871; Unassembled WGS sequence.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR CDD; cd07937; DRE_TIM_PC_TC_5S; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR003379; Carboxylase_cons_dom.
DR InterPro; IPR005776; OadA.
DR InterPro; IPR000891; PYR_CT.
DR InterPro; IPR011053; Single_hybrid_motif.
DR NCBIfam; TIGR01108; oadA; 1.
DR PANTHER; PTHR45266; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR PANTHER; PTHR45266:SF3; OXALOACETATE DECARBOXYLASE ALPHA CHAIN; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR Pfam; PF02436; PYC_OADA; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF89000; post-HMGL domain-like; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Lyase {ECO:0000313|EMBL:EFU67648.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032871}.
FT DOMAIN 5..265
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
FT DOMAIN 521..598
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 511..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 64523 MW; 2005BFD1FD56B785 CRC64;
MTKKIKMTEL VLRDAHQSLF ATRLRLDDML PIAQELDNIG YWSLEAWGGA TFDSCIRFLG
EDPWVRLREL KKACPKTPLQ MLLRGQNLLG YRHYADDVVE RFVERCVANG MDVFRVFDAL
NDPRNMKAAL QAVRKFGAHA QGTLSYTTSP VHTMQTWLDT TEQLLEIGID SLVIKDMSGI
LNPMAAADLV REIKKRFDVE LHLHCHSTTG MAEMALLKAI EAGVDGIDTA ISSMSGTYGH
PATESMVATL QGTEYDTGLD IPRLEKIAAY FRNVRKKYAK FEGQLRGVDS RILVAQVPGG
MLTNLENQLK QQNASDKLDL VLEEIPRVRK DLGYIPLVTP TSQIVGTQSV INVLTGERYK
TIAKETAGIL KGEYGKTPAP VDSALQARVL EGAAPVTDRP ADHIAPEIAK IEAEVAEQAK
VKGVKLADNA VDDALIVALF PQIAWKFLEN RNNPAAFEPA PTGNESAVEN KPVSKAAPAA
SGSAVYTVEL EGKAFVVKVS EGGDISHVAT TTPQAAPQAT PAPAPTSGGT PVTAPMAGNI
WKVVATEGQT VAAGDVLFIL EAMKMETEVK AAQAGTVRGI CVKTGDAVAV GDTVMNLV
//
