ID E6MDN7_9FIRM Unreviewed; 640 AA.
AC E6MDN7;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Glutamate--ammonia ligase, catalytic domain protein {ECO:0000313|EMBL:EFV02646.1};
DE EC=6.3.1.2 {ECO:0000313|EMBL:EFV02646.1};
GN Name=glnA {ECO:0000313|EMBL:EFV02646.1};
GN ORFNames=HMP0721_0119 {ECO:0000313|EMBL:EFV02646.1};
OS Pseudoramibacter alactolyticus ATCC 23263.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Pseudoramibacter.
OX NCBI_TaxID=887929 {ECO:0000313|EMBL:EFV02646.1, ECO:0000313|Proteomes:UP000004754};
RN [1] {ECO:0000313|EMBL:EFV02646.1, ECO:0000313|Proteomes:UP000004754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23263 {ECO:0000313|EMBL:EFV02646.1,
RC ECO:0000313|Proteomes:UP000004754};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV02646.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEQN01000005; EFV02646.1; -; Genomic_DNA.
DR AlphaFoldDB; E6MDN7; -.
DR STRING; 887929.HMP0721_0119; -.
DR eggNOG; COG3968; Bacteria.
DR HOGENOM; CLU_024307_0_0_9; -.
DR Proteomes; UP000004754; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EFV02646.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004754}.
FT DOMAIN 6..95
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 100..530
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 640 AA; 70651 MW; EEE29C5365B8937D CRC64;
MELGATHFTH WFQPMTGATA EKHDAFISPT DEGKVIMEFS GKELIKGEPD ASSFPSGGLR
ATFEARGYTA WDPTSFAFVK GKSLYIPTSF ISYSGEVLDK KTPLLRSMKA LSDEAIRILA
LFGKTDVKKV TTTVGAEQEY FLIDNDMYKK RKDLILTGRT LFGADAPKGQ EMEDHYFGRI
RGRVRHFMRE VDDELWALGV PSKTRHNEVA PCQHELAPVF STSNQATDNN HLIMETLRRI
APKHNLHCLI HKKPFEGING SGKHNNWAIS TDTGENLLDP GGDPASNLQF LLFLVAVIEA
VDRYPELLRS TVASAGNDHR LGGNEAPPAI ISIFLGDQLT AALKSLETGE TVETARDLIM
DIGVDSVPNF ISDATDRNRT SPFAFTGNKF EFRMLGSNQS IAGPNIALNA AVAEVLREYA
DALEGSTDFE ADCREFLRGR LSAHKRVIFN GNNYSDEWVA EAARRGLPNL KTTPEAFADY
CLPKNVDVMA RHGIYSEEEM KARQEIHLEE YAKTINIEAL TMLSMARHEI LPAVLKCEKD
LTTILAQKKA VGLDTKGSVE AKMAARISAL AGGMLEKTDA LEAANRAAQA AADAQERADA
YCNAVIGAMN ALRAVADELE TIVGREYWPY PIYEDLLFYV
//
